Non-contact behavioral study through intelligent image analysis is becoming increasingly vital in animal neuroscience and ethology. The shift from traditional "black box" methods to more open and intelligent approaches is driven by advances in deep l...
Municipal wastewater substantially contributes to aquatic ecological risks. Assessing the toxicity of municipal wastewater through dose-effect curves is challenging owing to the time-consuming, labor-intensive, and costly nature of biological assays....
BACKGROUND: Larval zebrafish phenotypes serve as critical research indicators in fields such as ecotoxicology and safety assessment since phenotypic defects are closely related to alterations of underlying pathway. However, identifying these defects ...
Hundreds of loci have been robustly associated with obesity-related traits, but functional characterization of candidate genes remains a bottleneck. Aiming to systematically characterize candidate genes for a role in accumulation of lipids in adipocy...
Over the past decades, exposure to per- and polyfluoroalkyl substances (PFAS), a group of synthetic chemicals notorious for their environmental persistence, has been shown to pose increased health risks. Despite that some PFAS were reported to have e...
Identifying new anti-seizure medications (ASMs) is difficult due to limitations in animal-based assays. Zebrafish (Danio rerio) serve as a model for chemical and genetic seizures, but current methods for detecting anti-seizure responses are limited b...
Zebrafish are widely used in vertebrate studies, yet minimally invasive individual tracking and identification in the lab setting remain challenging due to complex and time-variable conditions. Advancements in machine learning, particularly neural ne...
Revealing the evolved mechanisms that give rise to collective behavior is a central objective in the study of cellular and organismal systems. In addition, understanding the algorithmic basis of social interactions in a causal and quantitative way of...
Journal of pharmaceutical and biomedical analysis
40187127
An innovative, integrated strategy was developed for rapid and comprehensive quality assessment of Ligusticum chuanxiong Hort., the key raw material for Guanxinning tablets. This approach simultaneously evaluates both chemical composition and biologi...
Organophosphorus flame retardants (OPFRs) are important chemical additives that are used in commercial products. However, owing to increasing health concerns, the discovery of new OPFRs has become imperative. Herein, we propose an explainable artific...