Anesthesiology

Hybrid 3D/2D Convolutional Neural Network for Hemorrhage Evaluation on Head CT.

BACKGROUND AND PURPOSE: Convolutional neural networks are a powerful technology for image recognition. This study evaluates a convolutional neural network optimized for the detection and quantification of intraparenchymal, epidural/subdural, and subarachnoid hemorrhages on noncontrast CT.

A System for Automated Determination of Perioperative Patient Acuity.

The widely used American Society of Anesthesiologists Physical Status (ASA PS) classification is subjective, requires manual clinician review to score, and has limited granularity. Our objective was to develop a system that automatically generates an ASA PS with finer granularity by creating a continuous ASA PS score. Supervised machine learning methods were used to create a model that predicts a ...

The characteristic patterns of neuronal avalanches in mice under anesthesia and at rest: An investigation using constrained artificial neural networks.

Local perturbations within complex dynamical systems can trigger cascade-like events that spread across significant portions of the system. Cascades o...

Physicochemical stability of binary admixtures of paracetamol and dexketoprofen-trometamol for patient-controlled analgesia use.

BACKGROUND: Intravenous admixtures of dexketoprofen-trometamol and paracetamol are frequently used in clinical practice due to synergism obtained admi...

Deep Learning Solutions for Classifying Patients on Opioid Use.

Opioid analgesics, as commonly prescribed medications used for relieving pain in patients, are especially prevalent in US these years. However, an inc...

Using machine learning techniques to develop forecasting algorithms for postoperative complications: protocol for a retrospective study.

INTRODUCTION: Mortality and morbidity following surgery are pressing public health concerns in the USA. Traditional prediction models for postoperativ...

Bioactive polymeric formulations for wound healing.

Ricinoleic acid (RA) has potential to promote wound healing because of its analgesic and anti-inflammatory properties. This study investigates the syn...

Successful bystander-administered intranasal naloxone reversal of opioid overdose between two veterans: A case report.

Opioid overdose-related morbidity and mortality remain one of the most pressing public health crises. Overdose education and naloxone distribution hav...

A novel triterpenoid 16-hydroxy betulinic acid isolated from attributes multi-faced pharmacological activities.

The aerial parts of extensively used ethnomedicinal plant (Burm. f.) Robinson growing wild in Bangladesh were investigated to isolate and characteriz...

Tranexamic acid administration for anatomic and reverse total shoulder arthroplasty: a systematic review and meta-analysis.

BACKGROUND: Tranexamic acid (TXA) has been shown to reduce perioperative blood loss and risk of blood transfusion. Evidence establishing its efficacy ...

Prediction of opioid dose in cancer pain patients using genetic profiling: not yet an option with support vector machine learning.

OBJECTIVE: Use of opioids for pain management has increased over the past decade; however, inadequate analgesic response is common. Genetic variabilit...

Palliative analgesia with topical sevoflurane in cancer-related skin ulcers: a case report.

A Caucasian 39-year-old male patient with a poorly-differentiated infiltrating epidermoid penile carcinoma with urethral invasion was diagnosed. The p...

Improving the anesthetic process by a fuzzy rule based medical decision system.

OBJECTIVE: The main objective of this research is the design and implementation of a new fuzzy logic tool for automatic drug delivery in patients unde...

Pharmacokinetics of dexmedetomidine during analgosedation in ICU patients.

Dexmedetomidine (DEX) is a fairly new alfa-agonist which has been increasingly used in recent years for analgosedation, mostly because it offers a uni...

Comparison of Single-Shot Intrathecal Morphine Injection and Continuous Epidural Bupivacaine for Post-Operative Analgaesia after Elective Abdominal Hysterectomy.

BACKGROUND: Abdominal hysterectomy (AH) is painful. The aim of this study was to compare intrathecal morphine (ITM) and epidural bupivacaine (EB) for ...

Investigation of nepetolide as a novel lead compound: Antioxidant, antimicrobial, cytotoxic, anticancer, anti-inflammatory, analgesic activities and molecular docking evaluation.

In the present study, we describe various pharmacological effects and computational analysis of nepetolide, a tricyclic clerodane-type diterpene, isol...

The Combined Effects of Levothyroxine and Low Level Laser Therapy on Wound Healing in Hypothyroidism Male Rat Model.

Hypothyroidism is caused by inadequate production and storage of thyroid hormones. Hypothyroidism is associated with delayed wound healing. Laser the...

Simultaneous quantitative determination of bioactive terpene indole alkaloids in ethanolic extracts of Catharanthus roseus (L.) G. Don by ultra high performance liquid chromatography-tandem mass spectrometry.

A rapid, sensitive and reproducible method using ultra-high-performance liquid chromatography coupled with electrospray ionization hybrid triple quadr...

[Subcostal transversus abdominis plane block can improve analgesia after laparoscopic cholecystectomy].

BACKGROUND AND GOAL OF STUDY: After laparoscopic cholecystectomy, patients have moderate pain in the early postoperative period. Some studies shown be...

The Opioid Abuse Risk Screener predicts aberrant same-day urine drug tests and 1-year controlled substance database checks: A brief report.

The Opioid Abuse Risk Screener was developed to support well-informed decision-making in opioid analgesic prescribing by extending the breadth of psyc...