Bacterial Infection

Antimicrobial Activity of Tea and Agarwood Leaf Extracts Against Multidrug-Resistant Microbes.

Emerging multidrug-resistant (MDR) strains are the main challenges to the progression of new drug discovery. To diminish infectious disease-causing pathogens, new antibiotics are required while the drying pipeline of potent antibiotics is adding to the severity. Plant secondary metabolites or phytochemicals including alkaloids, phenols, flavonoids, and terpenes have successfully demonstrated their...

Sustainable nanomaterials: the role of Cyrene in optimising carbon nanotubes dispersion and filtration efficiency.

This study focuses on the fabrication and characterisation of single-walled carbon nanotube (SWCNT) buckypapers and polyethersulfone (PES) flat-sheet membranes using Cyrene, aiming toevaluate its efficacy as a green solvent for these applications. Pristine SWCNTs were dispersed inCyrene without surfactants and compared to N-Methyl-2-pyrrolidone (NMP) dispersions. Buckypapers were fabricated from t...

Biofilm architecture and dynamics of the oral ecosystem.

The oral cavity, being a nutritionally enriched environment, has been proven to be an ideal habitat for biofilm development. Various microenvironments...

NERVE 2.0: boosting the new enhanced reverse vaccinology environment via artificial intelligence and a user-friendly web interface.

BACKGROUND: Vaccines development in this millennium started by the milestone work on Neisseria meningitidis B, reporting the invention of Reverse Vacc...

Antimicrobial activity of L. Pers against periodontal pathogen: .

BACKGROUND: is widely recognised as a periodontal pathogen. In recent years, there has been growing interest in the use of medicinal plant extracts a...

Dysregulation of saliva and fecal microbiota as novel biomarkers of colorectal cancer.

The aim of this study was to investigate the biomarkers of salivary and fecal microbiota in Colorectal cancer (CRC). Initially, the study scrutinized ...

Research and application of intelligent diagnosis and treatment engineering bacteria.

For over a century, scientists have been harnessing the therapeutic potential of bacteria in treating diseases. The advent of synthetic biology in rec...

extract in combination with lytic phage cocktails: a promising therapeutic approach against biofilms of multi-drug resistant .

Antimicrobial resistance (AMR) poses a significant global threat to public health systems, rendering antibiotics ineffective in treating infectious di...

Harnessing lactic acid bacteria for nicotinamide mononucleotide biosynthesis: a review of strategies and future directions.

Nicotinamide mononucleotide (NMN), one of the crucial precursors of nicotinamide adenine dinucleotide, has garnered considerable interest for its phar...

Machine Learning-Assisted Liquid Crystal Optical Sensor Array Using Cysteine-Functionalized Silver Nanotriangles for Pathogen Detection in Food and Water.

The challenge of rapid identification of bacteria in food and water still persists as a major health problem. To tackle this matter, we have developed...

The native Iranian soil bacteria with high potential to produce extracellular methionine gamma-lyase.

This study aimed to screen native methionine gamma-lyase (L-methioninase) producing bacteria from soil samples and optimize the culture media for enha...

Antimicrobial Peptides as Broad-Spectrum Therapeutics: Computational Analysis to Identify Universal Physical-Chemical Features Responsible for Multitarget Activity.

Antimicrobial peptides (AMPs) hold significant potential as broad-spectrum therapeutics due to their ability to target a variety of different pathogen...

Possible biocontrol of bacterial blight in pomegranate using native endophytic spp. under field conditions.

Bacterial blight in pomegranate, caused by pv. (Xcp), is one of the most devastating diseases, leading to substantial economic losses in pomegranate...

Bacteriological load in Holstein Friesian cows with dystocia.

The research took place on a farm in North-Eastern Romania with Holstein Friesian cows aged between 3 and 9 years. Bacteriological investigations were...

Rapid diagnosis of bacterial vaginosis using machine-learning-assisted surface-enhanced Raman spectroscopy of human vaginal fluids.

UNLABELLED: Bacterial vaginosis (BV) is an abnormal gynecological condition caused by the overgrowth of specific bacteria in the vagina. This study ai...

Lipid discovery enabled by sequence statistics and machine learning.

Bacterial membranes are complex and dynamic, arising from an array of evolutionary pressures. One enzyme that alters membrane compositions through cov...

Comparative study of DCNN and image processing based classification of chest X-rays for identification of COVID-19 patients using fine-tuning.

The conventional detection of COVID-19 by evaluating the CT scan images is tiresome, often experiences high inter-observer variability and uncertainty...

Genomic analysis, culturing optimization, and characterization of bacteriophage OSYSP, previously studied as effective pathogen control on fresh produce.

Advances in bacteriophage genome sequencing and regulatory approvals of some bacteriophages in various applications have renewed interest in these ant...

Machine learning-enhanced assessment of potential probiotics from healthy calves for the treatment of neonatal calf diarrhea.

Neonatal calf diarrhea (NCD) remains a significant contributor to calf mortality within the first 3 weeks of life, prompting widespread antibiotic use...

Combined effect of Tetracycline compounds and essential oils on antimicrobial resistant isolated from the swine food chain.

Antimicrobial resistance (AMR) poses risks for food stakeholders because of the spread of resistant microbes and potential foodborne diseases. In exam...