COVID-19

Evaluation of a Urine-Based Rapid Molecular Diagnostic Test with Potential to Be Used at Point-of-Care for Pulmonary Tuberculosis: Cape Town Cohort.

Tuberculosis (TB) diagnosis among sputum-scarce patients is time consuming. Thus, a nonsputum diagnostic alternative is urgently needed. The Mycobacterium tuberculosis-specific transrenal (Tr) DNA from urine is a potential target for TB diagnostics. In this study, a new urine-based Tr-DNA molecular assay was evaluated for diagnosis of pulmonary tuberculosis among 428 adults suspected of having pul...

Stability of infliximab solutions in different temperature and dilution conditions.

Infliximab is a monoclonal antibody widely used for the treatment of inflammatory diseases. Over the past few years, many studies have assessed that monoclonal antibodies are prone to aggregation under stress conditions. The aim of this study was to investigate the stability of solutions of an infliximab biosimilar (Inflectra) at different concentrations (0.4, 2 and 10 mg/mL). These solutions were...

Verification and large scale clinical evaluation of a national standard protocol for Salmonella spp./Shigella spp. screening using real-time PCR combined with guided culture.

Salmonella spp./Shigella spp. are often associated with food poisoning and fecal-oral transmission of acute gastroenteritis that requires strict monit...

Aptamer facilitated purification of functional proteins.

DNA aptamers are attractive capture probes for affinity chromatography since, in contrast to antibodies, they can be chemically synthesized and, in co...

Molecular mechanism of apoptosis induction in Jurkat E6-1 cells by alkaloids extract.

The present study demonstrates apoptosis-inducing potential and mechanism of action of alkaloid extract in Jurkat E6-1 cancer cell line. Liquid Chrom...

The ability to predict pregnancy loss in cattle with ELISAs that detect pregnancy associated glycoproteins is antibody dependent.

The concentration of circulating pregnancy associated glycoproteins (PAGs) early in pregnancy may serve as markers to predict late embryonic mortality...

Augmented reality for personalized nanomedicines.

As our understanding of onset and progress of diseases at the genetic and molecular level rapidly progresses, the potential of advanced technologies, ...

First study in Qatar to reveal high Legionella counts in cooling towers.

Legionella spp. is transmitted from water to humans by aerosol-generating devices, including cooling towers (CTs). There have not been published repor...

Lyme disease presenting with facial palsy and myocarditis mimicking myocardial infarction.

A 45-year-old woman presented with a sudden episode of typical chest pain, radiating to her neck. The patient denied premature coronary artery disease...

Species composition of and fumonisin production by the Fusarium fujikuroi species complex isolated from Korean cereals.

To assess the risk of fumonisin contamination in Korean cereals, we isolated colonies of the Fusarium fujikuroi species complex (FFSC) from barley, ma...

Hierarchical Nanogold Labels to Improve the Sensitivity of Lateral Flow Immunoassay.

Lateral flow immunoassay (LFIA) is a widely used express method and offers advantages such as a short analysis time, simplicity of testing and result ...

Pro-apoptotic and Anti-migratory Effects of L. Plant Extracts on the Human Prostate Cancer Cell Lines PC3.

This study aims to evaluate the cytotoxic and anti-migratory effects of L. on prostate cancer cells, identify the active compound/s and characterize...

Serum Vitamin D Levels Affect Pathologic Complete Response in Patients Undergoing Neoadjuvant Systemic Therapy for Operable Breast Cancer.

INTRODUCTION: There has been increasing interest in the potential benefit of vitamin D in improving breast cancer outcome. Preclinical studies suggest...

Principal component reconstruction (PCR) for cine CBCT with motion learning from 2D fluoroscopy.

PURPOSE: This work aims to generate cine CT images (i.e., 4D images with high-temporal resolution) based on a novel principal component reconstruction...

Examination of Quaternary Ammonium Compound Resistance in Isolated from Cooked Meat Products in China.

The aim of this study was to examine the presence of genes responsible for resistance to quaternary ammonium compounds (QACs) and the association of ...

Isolation of in HUVEC line.

formerly named and ' Rickettsia amblyommii' is an intracellular bacterium belonging to the spotted fever group It is highly prevalent in and in ot...

Zinc-Modified Nanotransporter of Doxorubicin for Targeted Prostate Cancer Delivery.

This work investigated the preparation of chitosan nanoparticles used as carriers for doxorubicin for targeted cancer delivery. Prepared nanocarriers ...

Angiotensin-(1-7) Inhibits Thrombin-Induced Endothelial Phenotypic Changes and Reactive Oxygen Species Production via NADPH Oxidase 5 Downregulation.

The angiotensin-(1-7)/angiotensin-converting enzyme 2/Mas receptor axis counter-regulates the detrimental effects of angiotensin II. Beneficial effec...

Screening and Detecting in Different Food Matrices in Southern Tunisia Using a Combined Enrichment/Real-Time PCR Method: Correlation with Conventional Culture Method.

A combined enrichment/ newly developed TaqMan real-time PCR (qPCR) method as a screening assay to detect spp. in 500 naturally food matrices is eval...

Nanoparticle based bio-bar code technology for trace analysis of aflatoxin B1 in Chinese herbs.

A novel and sensitive assay for aflatoxin B1 (AFB1) detection has been developed by using bio-bar code assay (BCA). The method that relies on polyclon...