Infectious Disease

COVID-19

Latest AI and machine learning research in covid-19 for healthcare professionals.

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Real-time detection and localization of honeycomb defects in concrete pillars using hybrid deep learning models.

This paper presents a hybrid model based on deep learning for the detection and instance segmentation of defects in honeycombs of concrete structures with YOLOv5 and Mask R-CNN. The approach combines the fast object detection feature of YOLOv5 with the precise instance segmentation feature of Mask R-CNN to effectively resolve and localize defect areas in structural images. A silicon dataset contai...

Jul 2 2025 40593085

Comprehensive machine learning analysis of PANoptosis signatures in multiple myeloma identifies prognostic and immunotherapy biomarkers.

PANoptosis is closely associated with tumorigenesis and therapeutic response, yet its role in multiple myeloma (MM) remains unclear. This study analyzed bulk transcriptomic and clinical data from the TCGA and GEO databases to identify seven PANoptosis-related genes (PRGs) using machine learning (LASSO regression and random forest models) and univariate Cox analysis, and constructed a prognostic ri...

Jul 2 2025 40594894
Identification of key biomarkers and potential therapeutic drugs in nasopharyngeal carcinoma based on comprehensive bioinformatics analysis.

Nasopharyngeal carcinoma (NPC) is the most prevalent type of head- and -neck cancer, and its diagnosis and treatment are currently facing significant ...

Jul 1 2025 40591047
Language models learn to represent antigenic properties of human influenza A(H3) virus.

Given that influenza vaccine effectiveness depends on a good antigenic match between the vaccine and circulating viruses, it is important to assess th...

Jul 1 2025 40592976
Screening biomarkers related to cholesterol metabolism in osteoarthritis based on transcriptomics.

Cholesterol metabolism-related genes (CMRGs) have been associated with osteoarthritis (OA), but their specific regulatory mechanisms remain unclear. T...

Jul 1 2025 40593053
Identifying real time surveillance indicators to estimate COVID-19 hospital admissions in Colorado during and after the public health emergency.

Questions remain about how best to focus surveillance efforts for COVID-19 and other emerging respiratory diseases. We used an archive of COVID-19 dat...

Jul 1 2025 40593931
Leveraging federated learning and edge computing for pandemic-resilient healthcare.

The universal demand for the development and deployment of responsive medical infrastructure and damage control techniques, including the application ...

Jul 1 2025 40593962
Artificial intelligence derived grading of mustard gas induced corneal injury and opacity.

Artificial intelligence (AI) has emerged as a transformative tool in ophthalmology for disease diagnosis and prognosis. However, use of AI for assessi...

Jul 1 2025 40594758
Identification of key genes associated with cellular aging and mitochondria in acute myocardial infarction.

Acute myocardial infarction (AMI) poses a significant global mortality burden. Utilizing bio informatics, this study explored cellular aging-related g...

Jul 1 2025 40594763
Generative AI for weakly supervised segmentation and downstream classification of brain tumors on MR images.

Segmenting abnormalities is a leading problem in medical imaging. Using machine learning for segmentation generally requires manually annotated segmen...

Jul 1 2025 40594922
Automatic cattle identification system based on color point cloud using hybrid PointNet++ Siamese network.

Cattle health monitoring and management systems are essential for farmers and veterinarians, as traditional manual health checks can be time-consuming...

Jul 1 2025 40595167
Identification of CXCR4 as a potential preventive gene in clear cell renal cell carcinoma from machine learning and immune analysis.

Clear cell renal cell carcinoma (ccRCC) represents a prevalent malignant kidney tumor characterized by high metastatic potential and recurrence rates....

Jul 1 2025 40595325
A novel feature extractor based on constrained cross network for detecting sleep state.

With increasing awareness of healthy living and social pressure, more and more people have begun to pay attention to their sleep state. Most existing ...

Jul 1 2025 40595334
Mitochondrial haplogroup A2 is associated with increased COVID-19 mortality in an admixed Brazilian population.

Mitochondria play a crucial role in cellular respiration and immune responses. Mitochondrial DNA (mtDNA) haplogroups and variants have been associated...

Jul 1 2025 40595775
Predict the degree of secondary structures of the encoding sequences in DNA storage by deep learning model.

DNA storage has been widely considered as a promising alternative for exponentially growing data. However, the inherent complex secondary structures s...

Jul 1 2025 40596218
Profiling short-term longitudinal severity progression and associated genes in COVID-19 patients using EHR and single-cell analysis.

Here we propose CovSF, a deep learning model designed to track and forecast short-term severity progression of COVID-19 patients using longitudinal cl...

Jul 1 2025 40596577
Multi-dimensional annotation of porcine variants using genomic and epigenomic features in pigs.

BACKGROUND: Investigating the functional impact of genomic variants is essential to uncover the molecular mechanisms behind complex traits. This study...

Jul 1 2025 40598185
An MOF-Enhanced Anti-Fouling Immunoprobe Platform for Efficient Direct Screening of Pancreatic Cancer.

Monitoring biomarkers offers insights for early disease (e.g., cancer, chronic diseases) screening, treatment guidance and response evaluation. To tac...

Jul 1 2025 40598854
Antimicrobial peptides: An important link in the game theory between plants and pathogens.

BACKGROUND: Antimicrobial peptides (AMPs) are peptides produced by organisms during the evolutionary process to defend themselves against external bio...

Jun 29 2025 40592369
AntiBMPNN: Structure-Guided Graph Neural Networks for Precision Antibody Engineering.

Antibodies are crucial for medical applications, yet traditional methods for designing sequences are inefficient. This study introduces AntiBMPNN, an ...

Jun 27 2025 40576473
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