Infectious Disease

Flu & URI

Latest AI and machine learning research in flu & uri for healthcare professionals.

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Transfer learning improves pMHC kinetic stability and immunogenicity predictions.

The cellular immune response comprises several processes, with the most notable ones being the binding of the peptide to the Major Histocompability Complex (MHC), the peptide-MHC (pMHC) presentation to the surface of the cell, and the recognition of the pMHC by the T-Cell Receptor. Identifying the most potent peptide targets for MHC binding, presentation and T-cell recognition is vital for develop...

Dec 21 2023 38577265

Structure-based approaches against COVID-19.

The coronavirus disease 2019 (COVID-19) pandemic has had a major impact on human life. This review highlights the versatile roles of both classical and modern structure-based approaches for COVID-19. X-ray crystallography, nuclear magnetic resonance spectroscopy, and cryogenic electron microscopy are the three cornerstones of classical structural biology. These technologies have helped provide fun...

Dec 20 2023 38305483
Humoral Immune Responses after an Omicron-Adapted Booster BNT162b2 Vaccination in Patients with Lymphoid Malignancies.

To accommodate waning COVID-19 vaccine immunity to emerging SARS-CoV-2 variants, variant-adapted mRNA vaccines have been introduced. Here, we examine ...

Dec 20 2023 38275946
Epidemiological and viral studies of rabies in Bali, Indonesia.

BACKGROUND AND AIM: Rabies has been endemic in Bali since 2009, and cases has recently increased. Unfortunately, there is a lack of available vaccines...

Dec 20 2023 38328353
Predicting COVID-19 pandemic waves including vaccination data with deep learning.

INTRODUCTION: During the recent COVID-19 pandemics, many models were developed to predict the number of new infections. After almost a year, models ha...

Dec 15 2023 38162619
Optimizing Signal Management in a Vaccine Adverse Event Reporting System: A Proof-of-Concept with COVID-19 Vaccines Using Signs, Symptoms, and Natural Language Processing.

INTRODUCTION: The Vaccine Adverse Event Reporting System (VAERS) has already been challenged by an extreme increase in the number of individual case s...

Dec 7 2023 38062261
Efficient delivery of the immunodominant genes of African swine fever virus by adeno-associated virus serotype 2.

BACKGROUND AND AIM: Adeno-associated virus serotype 2 (AAV2) represents a promising basis for developing a virus-vector vaccine against African swine ...

Dec 6 2023 38328367
Prediction of the number of asthma patients using environmental factors based on deep learning algorithms.

BACKGROUND: Air pollution, weather, pollen, and influenza are typical aggravating factors for asthma. Previous studies have identified risk factors us...

Dec 1 2023 38041105
Antibacterial and Antiviral Properties of Essential Oil.

The Korean mountains are home to the Korean red pine (). Pine needle oil has been used as a food additive and a traditional herbal medicine; however, ...

Nov 27 2023 38231728
Simultaneous Quantitative Determination of Low-Concentration Preservatives and Heavy Metals in Tricholoma Matsutakes Based on SERS and FLU Spectral Data Fusion.

As an ingredient of great economic value, Tricholoma matsutake has received widespread attention. However, heavy metal residues and preservatives in i...

Nov 26 2023 38231731
COVID-19 Vaccination in Liver Cirrhosis: Safety and Immune and Clinical Responses.

INTRODUCTION: Three years after the beginning of the SARS-CoV-2 pandemic, the safety and efficacy of COVID-19 vaccination in liver cirrhosis (LC) pati...

Nov 15 2023 39360169
Artificial intelligence-driven systems engineering for next-generation plant-derived biopharmaceuticals.

Recombinant biopharmaceuticals including antigens, antibodies, hormones, cytokines, single-chain variable fragments, and peptides have been used as va...

Nov 15 2023 38034587
The smarty4covid dataset and knowledge base as a framework for interpretable physiological audio data analysis.

Harnessing the power of Artificial Intelligence (AI) and m-health towards detecting new bio-markers indicative of the onset and progress of respirator...

Nov 6 2023 37932314
A novel deep generative model for mRNA vaccine development: Designing 5' UTRs with 1-methyl-pseudouridine modification.

Efficient translation mediated by the 5' untranslated region (5' UTR) is essential for the robust efficacy of mRNA vaccines. However, the 1-methyl-pse...

Nov 5 2023 38572113
Preclinical efficacy of a cell division protein candidate gonococcal vaccine identified by artificial intelligence.

Vaccines to curb the global spread of multidrug-resistant gonorrhea are urgently needed. Here, 26 vaccine candidates identified by an artificial intel...

Oct 31 2023 37905891
Effect of SARS-CoV-2 spike protein exposure on ACE2 and interleukin 6 productions in human adipocytes: An in-vitro study.

Since adipocytes play a crucial role in pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection due to their interactio...

Oct 29 2023 38455635
CLCAP: Contrastive learning improves antigenicity prediction for influenza A virus using convolutional neural networks.

Influenza viruses are detected year-round over the world and the viruses will usually circulate during fall and winter, causing the seasonal flu. The ...

Oct 27 2023 39491098
Screening COVID-19 by Swaasa AI platform using cough sounds: a cross-sectional study.

The Advent of Artificial Intelligence (AI) has led to the use of auditory data for detecting various diseases, including COVID-19. SARS-CoV-2 infectio...

Oct 25 2023 37880351
Influenza Epidemic Trend Surveillance and Prediction Based on Search Engine Data: Deep Learning Model Study.

BACKGROUND: Influenza outbreaks pose a significant threat to global public health. Traditional surveillance systems and simple algorithms often strugg...

Oct 17 2023 37847532
Using artificial intelligence algorithms to predict the overall survival of hemodialysis patients during the COVID-19 pandemic: A prospective cohort study.

BACKGROUND: Hemodialysis (HD) patients are a vulnerable population at high risk for severe complications from COVID-19. The impact of partial COVID-19...

Sep 15 2023 37713313
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