Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 568-588 of 10,353 articles
Identification of shared mechanisms between Alzheimer's disease and atherosclerosis by integrated bioinformatics analysis.

Alzheimer's disease (AD) and atherosclerosis (AS) are two interacting diseases mostly affecting aged...

Analysing protein complexes in plant science: insights and limitation with AlphaFold 3.

AlphaFold 3 (AF3), an artificial intelligence (AI)-based software for protein complex structure pred...

Integration of machine learning and bulk sequencing revealed exosome-related gene FOSB was involved in the progression of abdominal aortic aneurysm.

BACKGROUND: Abdominal aortic aneurysm (AAA), characterized by the pathological dilation of the abdom...

Metabolic profiles in laryngeal cancer defined two distinct molecular subtypes with divergent prognoses.

BACKGROUND: Laryngeal cancer (LCA) is the second most common type of head and neck malignancy, chara...

Meta-analysis of shotgun sequencing of gut microbiota in obese children with MASLD or MASH.

Alterations in the gut microbiome affect the development and severity of metabolic dysfunction-assoc...

Advancing Traditional Dunhuang Regional Pattern Design with Diffusion Adapter Networks and Cross-Entropy.

To promote the inheritance of traditional culture, a variety of emerging methods rooted in machine l...

RNAcare: integrating clinical data with transcriptomic evidence using rheumatoid arthritis as a case study.

BACKGROUND: Gene expression analysis is a crucial tool for uncovering the biological mechanisms that...

The Role of HbA1c in Parkinson's Disease: An Integrative Analysis by Single-Cell, Bulk Transcriptome and Mendelian Randomization.

Decreased glucose tolerance is recognized as a factor associated with Parkinson's disease (PD) progr...

Making Sense of Missense: Benchmarking MutScore for Variant Interpretation in Inherited Cardiac Diseases.

BACKGROUND: Accurate interpretation of genetic variants still represents a major challenge. Accordin...

Intent to Cure: The Need for a Rare Disease Platform in India and Across the Global South.

The democratization of genomic technologies presents substantial opportunities for addressing rare g...

Investigating the paternal genetic structure and migration history of Chinese Qiang minority by Y-chromosome short tandem repeats.

Known for its legendary history and peculiar culture, Chinese Qiang minority aroused interest among ...

Non-invasive prediction of DCE-MRI radiomics model on CCR5 in breast cancer based on a machine learning algorithm.

BackgroundNon-invasive methods with universal prognostic guidance for detecting breast cancer (BC) s...

Imaging patterns and recommendations for diagnosis, staging, and management of lung cancer.

Lung cancer is the second most commonly diagnosed cancer worldwide. In the present era of targeted t...

A pathway-informed disease-related gene identification approach and its application to screen novel risk genes for Alzheimer's disease.

BACKGROUND: Alzheimer's disease (AD) is a severe neurodegenerative disorder, yet its molecular mecha...

Microbial vitamin biosynthesis links gut microbiota dynamics to chemotherapy toxicity.

Dose-limiting toxicities pose a major barrier to cancer treatment. While preclinical studies show th...

Integrating Artificial Intelligence and Precision Therapeutics for Advancing the Diagnosis and Treatment of Age-Related Macular Degeneration.

Age-related macular degeneration (AMD) is a multifactorial retinal disease influenced by complex mol...

CMImpute: cross-species and tissue imputation of species-level DNA methylation samples across mammalian species.

The large-scale application of the mammalian methylation array has substantially expanded the availa...

An artificial intelligence-based model for prediction of clonal hematopoiesis variants in cell-free DNA samples.

Circulating tumor DNA is a critical biomarker in cancer diagnostics, but its accurate interpretation...

XVir: A Transformer-Based Architecture for Identifying Viral Reads from Cancer Samples.

It is estimated that approximately 15% of cancers worldwide can be linked to viral infections. The v...

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