Genetics

Latest AI and machine learning research in genetics for healthcare professionals.

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Showing 7481-7500 of 14,220 articles

Semi-supervised learning for genomic prediction of novel traits with small reference populations: an application to residual feed intake in dairy cattle.

BACKGROUND: Genomic prediction for novel traits, which can be costly and labor-intensive to measure, is often hampered by low accuracy due to the limited size of the reference population. As an option to improve prediction accuracy, we introduced a semi-supervised learning strategy known as the self-training model, and applied this method to genomic prediction of residual feed intake (RFI) in dair...

Nov 7 2016 27821057

Both Phenolic and Non-phenolic Green Tea Fractions Inhibit Migration of Cancer Cells.

Green tea consumption is associated with chemoprevention of many cancer types. Fresh tea leaves are rich in polyphenolic catechins, which can constitute up to 30% of the dry leaf weight. While the polyphenols of green tea have been well investigated, it is still largely unknown, whether or not non-phenolic constituents also reveal chemopreventive and anti-metastatic effects. In this study, we inve...

Nov 3 2016 28194107
Comprehensive analysis of epigenetically regulated genes in anergic T cells.

T cell anergy is one of the important mechanisms for immune tolerance. The results of many studies investigating the mechanism for T cell anergy induc...

Nov 2 2016 27839672
Multidrug Resistant Causing Prosthetic Valve Endocarditis: A Genetic-Based Chronicle of Evolving Antibiotic Resistance.

 Successful treatment of infections caused by multidrug-resistant (MDR) is thwarted by the emergence of antibiotic resistance and biofilm formation ...

Oct 21 2016 29057280
Application of artificial neural network model combined with four biomarkers in auxiliary diagnosis of lung cancer.

The purpose of the study was to explore the application of artificial neural network model in the auxiliary diagnosis of lung cancer and compare the e...

Oct 20 2016 27766520
Genotoxic effects of synthetic amorphous silica nanoparticles in the mouse lymphoma assay.

Synthetic amorphous silica nanoparticles (SAS NPs) have been used in various industries, such as plastics, glass, paints, electronics, synthetic rubbe...

Oct 20 2016 28959608
Integrating network, sequence and functional features using machine learning approaches towards identification of novel Alzheimer genes.

BACKGROUND: Alzheimer's disease (AD) is a complex progressive neurodegenerative disorder commonly characterized by short term memory loss. Presently n...

Oct 18 2016 27756223
Predicting the Organelle Location of Noncoding RNAs Using Pseudo Nucleotide Compositions.

Noncoding RNAs (ncRNAs) are implicated in various biological processes. Recent findings have demonstrated that the function of ncRNAs correlates with ...

Oct 13 2016 27739055
Desktop Genetics.

Desktop Genetics is a bioinformatics company building a gene-editing platform for personalized medicine. The company works with scientists around the ...

Oct 13 2016 28757882
Transcriptomic alterations in Sitophilus zeamais in response to allyl isothiocyanate fumigation.

To study the fumigation mechanisms of Allyl isothiocyanate (AITC) a promising biorational alternative to present fumigants (phosphine and methyl bromi...

Oct 11 2016 28364805
Predicting Protein-DNA Binding Residues by Weightedly Combining Sequence-Based Features and Boosting Multiple SVMs.

Protein-DNA interactions are ubiquitous in a wide variety of biological processes. Correctly locating DNA-binding residues solely from protein sequenc...

Oct 11 2016 27740495
Virtual screening of natural compounds as inhibitors of EGFR 696-1022 T790M associated with non-small cell lung cancer.

Non-small cell lung cancer (NSCLC) is the most dominating and lethal type of lung cancer triggering more than 1.3 million deaths per year. The most ef...

Oct 10 2016 28293073
Inferring Unknown Biological Function by Integration of GO Annotations and Gene Expression Data.

Characterizing genes with semantic information is an important process regarding the description of gene products. In spite that complete genomes of m...

Oct 7 2016 27723603
Predicting proprotein convertase subtilisin kexin type-9 loss of function mutations using plasma PCSK9 concentration.

BACKGROUND: Low plasma proprotein convertase subtilisin kexin type-9 (PCSK9) concentration has been associated with loss of function (LOF) PCSK9 mutat...

Oct 3 2016 28391911
A comparative analysis of chaotic particle swarm optimizations for detecting single nucleotide polymorphism barcodes.

OBJECTIVE: Evolutionary algorithms could overcome the computational limitations for the statistical evaluation of large datasets for high-order single...

Sep 30 2016 27926379
A novel fuzzy set based multifactor dimensionality reduction method for detecting gene-gene interaction.

BACKGROUND: Gene-gene interaction (GGI) is one of the most popular approaches for finding the missing heritability of common complex traits in genetic...

Sep 29 2016 27765491
Why Are There Developmental Stages in Language Learning? A Developmental Robotics Model of Language Development.

Most theories of learning would predict a gradual acquisition and refinement of skills as learning progresses, and while some highlight exponential gr...

Sep 28 2016 27680660
Improving information retrieval in functional analysis.

Transcriptome analysis is essential to understand the mechanisms regulating key biological processes and functions. The first step usually consists of...

Sep 24 2016 27723507
MiRNATIP: a SOM-based miRNA-target interactions predictor.

BACKGROUND: MicroRNAs (miRNAs) are small non-coding RNA sequences with regulatory functions to post-transcriptional level for several biological proce...

Sep 22 2016 28185545
A Novel Hybrid Feature Selection Model for Classification of Neuromuscular Dystrophies Using Bhattacharyya Coefficient, Genetic Algorithm and Radial Basis Function Based Support Vector Machine.

An accurate classification of neuromuscular disorders is important in providing proper treatment facilities to the patients. Recently, the microarray ...

Sep 17 2016 27637476
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