Infectious Disease

Hepatitis

Latest AI and machine learning research in hepatitis for healthcare professionals.

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Mechanism of glucocerebrosidase activation and dysfunction in Gaucher disease unraveled by molecular dynamics and deep learning.

The lysosomal enzyme glucocerebrosidase-1 (GCase) catalyzes the cleavage of a major glycolipid gluco...

Feb 2019 30808805
AntiVPP 1.0: A portable tool for prediction of antiviral peptides.

Viruses are worldwide pathogens with a high impact on the human population. Despite the constant eff...

Feb 2019 30802694
Hepatitis Screening and Treatment Campaign in Malaysia-Validation of Low-cost Point of Care Screening Tests and Nucleic Acid Tests for Hepatitis B and C.

BACKGROUND: Two major challenges in implementing budget-constrained Hepatitis screening and treatmen...

Feb 2019 30828549
Machine Learning-based Development and Validation of a Scoring System for Screening High-Risk Esophageal Varices.

BACKGROUND & AIMS: Many patients with cirrhosis who undergo esophagogastroduodenoscopy (EGD) screeni...

Jan 2019 30708109
Machine learning models to predict disease progression among veterans with hepatitis C virus.

BACKGROUND: Machine learning (ML) algorithms provide effective ways to build prediction models using...

Jan 2019 30608929
Treatment With Grazoprevir/Elbasvir for Renal Transplant Recipients With Chronic Hepatitis C Virus Infection and Impaired Allograft Function.

BACKGROUND: Direct-acing antiviral agents are highly efficient treatment options for chronic hepatit...

Dec 2018 30656217
Data-driven supervised learning of a viral protease specificity landscape from deep sequencing and molecular simulations.

Biophysical interactions between proteins and peptides are key determinants of molecular recognition...

Dec 2018 30587591
Extracellular Vesicles from Amnion-Derived Mesenchymal Stem Cells Ameliorate Hepatic Inflammation and Fibrosis in Rats.

BACKGROUND: There are no approved drug treatments for liver fibrosis and nonalcoholic steatohepatiti...

Dec 2018 30675167
Acute Retroviral Syndrome Presenting as Acute Hepatitis.

Acute retroviral syndrome (ARS) can present as a wide array of clinical manifestations. Establishing...

Dec 2018 30820375
Structured illumination microscopy combined with machine learning enables the high throughput analysis and classification of virus structure.

Optical super-resolution microscopy techniques enable high molecular specificity with high spatial r...

Dec 2018 30543181
Functional expression of porcine interferon-α using a combinational strategy in Pichia pastoris GS115.

Porcine interferon-α (pIFN-α) could be used as the vaccine adjuvant to enhance the antiviral ability...

Dec 2018 30638508
Application of Machine Learning Methods to Predict Non-Alcoholic Steatohepatitis (NASH) in Non-Alcoholic Fatty Liver (NAFL) Patients.

Non-alcoholic fatty liver disease (NAFLD) is the leading cause of chronic liver disease worldwide. N...

Dec 2018 30815083
CbpM and CbpG of Streptococcus Pneumoniae Elicit a High Protection in Mice Challenged with a Serotype 19F Pneumococcus.

Among many pneumococcal antigens, choline-binding proteins (CPBs) display a high immunogenicity in a...

Dec 2018 30644702
Immunogenicity of Concentrated and Purified Inactivated Avian Influenza Vaccine Formulation.

Avian influenza (AI) H9N2 is a low pathogenic virus subtype belonging to Orthomyxoviridae family. Gi...

Dec 2018 31077122
Identification of Immune Signatures of Novel Adjuvant Formulations Using Machine Learning.

Adjuvants have long been critical components of vaccines, but the exact mechanisms of their action a...

Nov 2018 30504893
Machine learning methods for leveraging baseline covariate information to improve the efficiency of clinical trials.

Clinical trials are widely considered the gold standard for treatment evaluation, and they can be hi...

Nov 2018 30474289
Evaluation of serum and salivary interferon-γ levels in patients with oral lichen planus: a systematic review and meta-analysis of case-control studies.

OBJECTIVE: Cytokines have regulatory and leading roles in the immunopathogenesis of oral lichen plan...

Nov 2018 30642701
Ritonavir-boosted paritaprevir, ombitasvir plus ribavirin could improve eGFR in patients with renal impairment and HCV: an Egyptian cohort.

BACKGROUND: The present study aimed at evaluation of changes in estimated glomerular filtration rate...

Nov 2018 30791838
[Hepatitis B and renal failure: prevalence and associated factors in National University Hospital Center of Cotonou].

INTRODUCTION: the association between the kidneys and hepatitis B is complex. This study aims to det...

Oct 2018 31037181
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