Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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Where Your Eyes Go: How AI Output Design Impacts Reading Behavior.

The purpose was to examine how variations in AI output design affect radiologists' performance in interpreting chest X-rays. Eight readers interpreted 80 COVID-19 chest images under five AI conditions in this retrospective study: no feedback, one-word summary, graph, heatmap, and heatmap + graph. Reader accuracy and eye-tracking data were analyzed to assess diagnostic performance and efficiency. P...

Jun 29 2026 42371278

Operationalizing Digital Health Equity in Artificial Intelligence-Enabled Patient Decision Aids for Older Adults: Mixed Methods Study.

BACKGROUND: Artificial intelligence-enabled patient decision aids (AI-PDAs) hold promise for supporting older adults with chronic diseases in accessing personalized health information, clarifying preferences, and engaging in shared decision-making. Achieving equity in their design requires attention to the complex health care and digital contexts in which these tools are used. While the Digital He...

Jun 29 2026 42372250
Evaluation of a Digital Intervention for Monitoring and Improving Medication Adherence Among Real-World e-Consumers of HIV Preexposure Prophylaxis in China: Protocol for a Randomized Controlled Trial.

BACKGROUND: Preexposure prophylaxis (PrEP) is a key biomedical HIV prevention strategy that relies heavily on adherence for optimal effectiveness. In ...

Jun 29 2026 42372256
Antimicrobial peptide hydrogel delivery systems: Design strategies and functional expansion.

Antimicrobial peptides (AMPs), owing to their unique membrane-disrupting mechanism and low susceptibility to resistance, represent important candidate...

Jun 29 2026 42372463
A computational method to design broad-spectrum T cell-inducing vaccines applied to Betacoronaviruses.

Antigenically diverse pathogens such as coronaviruses pose substantial global health threats, highlighting the need for broad-spectrum vaccines. Here,...

Jun 29 2026 42372721
Gut microbial signature for frailty discrimination: a metagenomic meta-analysis of 28 independent cohorts.

Frailty, a clinical syndrome of multisystem decline and homeostatic vulnerability, is a critical public health priority. While the gut microbiome regu...

Jun 29 2026 42372926
Bacterial keratitis: a global review of current practices, challenges and innovations.

Bacterial keratitis is a major cause of corneal blindness worldwide, with marked differences in clinical presentation and risk factors across regions....

Jun 29 2026 42373310
Prediction of severe pediatric community-acquired pneumonia using multimodal fusion of chest radiographs and clinical data.

BACKGROUND: Community-acquired pneumonia (CAP) is a leading cause of morbidity and mortality in children, particularly in low-income countries. Severe...

Jun 29 2026 42374289
Glycemic variability does not provide incremental prognostic value for in-hospital death in community-acquired pneumonia patients: conventional clinical variables dominate.

OBJECTIVES: This study aimed to systematically evaluate whether glycemic variability (GV) could provide independent incremental prognostic value for i...

Jun 29 2026 42374364
Mapping the intellectual landscape of malaria drug repurposing: a systematic analysis of the 51 most cited studies.

BACKGROUND: The escalating threat of Plasmodium falciparum resistance to artemisinin-based therapies necessitates accelerated drug development. Drug r...

Jun 29 2026 42374402
Deep learning analysis of 12-lead electrocardiograms for bloodstream infection prediction: a multi-center validation study.

BACKGROUND: Prompt diagnosis of bloodstream infections (BSIs) is critical for antimicrobial stewardship but hindered by blood culture delays of 48 h o...

Jun 29 2026 42374403
Forecasting COVID-19 new cases using NBEATS deep learning and mobility data.

COVID-19 is a highly contagious disease transmitted primarily through human contact. Therefore, understanding population mobility is essential for pre...

Jun 29 2026 42371947
Nanocarrier-Based Gene Delivery Systems: Mechanisms, Clinical Translation, and Future Perspectives.

Gene therapy holds revolutionary potential for managing genetic disorders, cancers and infectious illnesses. However, one of the biggest challenges is...

Jun 28 2026 42366709
Calcineurin-Dependent Stress Adaptation Enables Caspofungin Heteroresistance Leading to Stable Resistance in Candida Glabrata.

Antifungal heteroresistance has emerged as a clinical challenge across diverse species. In Candida glabrata, however, it has rarely been reported. Her...

Jun 28 2026 42365577
Exploring feature limitations in antimicrobial resistance prediction: machine learning and deep learning in A. baumannii.

Antimicrobial resistance phenotype prediction (AMRPP) provides a computational alternative to conventional susceptibility testing. While most studies ...

Jun 28 2026 42366192
Pathogenic Significance of Trypanosomatids: Progress in Drug Resistance, Control Strategies, and Artificial Intelligence.

Trypanosomatids, including the genera Trypanosoma and Leishmania, are protozoan parasites of significant medical and veterinary relevance. These organ...

Jun 28 2026 42371586
Equity-by-design for socially assistive robots as digital health tools.

OBJECTIVES: To propose an equity-by-design agenda for socially assistive robots (SARs) as embodied digital health informatics interventions. MATERIALS...

Jun 27 2026 42364080
Differential Effects of Prenatal Depression and Anxiety on Infant Sleep: Dual-Pathway Mechanisms Involving the HPA Axis and the Gut-Brain Axis.

STUDY OBJECTIVES: Prenatal psychological distress is associated with adverse offspring outcomes, including infant sleep disturbances and altered gut m...

Jun 27 2026 42364158
Artificial intelligence-enhanced nurse navigation for monitoring and care of long COVID.

INTRODUCTION: Long COVID is a multisystem condition with challenging diagnosis. Nurse-navigation, a patient-centered intervention, can enhance educati...

Jun 27 2026 42364466
TACE-induced liver injury in hepatocellular carcinoma: mechanisms, prediction, and prevention in the era of gut microbiota and inflammasome research.

Transarterial chemoembolization (TACE) is a cornerstone locoregional therapy for hepatocellular carcinoma (HCC), yet most candidates also have cirrhos...

Jun 27 2026 42364906
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