Latest AI and machine learning research in infectious disease for healthcare professionals.
BACKGROUND: Emerging zoonotic poxviruses such as lumpy skin disease virus (LSDV) and monkeypox pose significant threats to animal and human health, yet validated antiviral targets remain scarce. Variola virus, the causative agent of smallpox, also belongs to the Poxviridae family, emphasizing the importance of preparedness against potential re-emergence. METHODS: We developed an AI-Enabled structu...
BACKGROUND: The Frailty in Tuberculosis (FIT) study aims to assess frailty in older adults with tuberculosis (TB) using machine learning (ML) to develop diagnostic models to identify prevalent frailty. Despite its relevance, limited research exists on frailty among this population, and the potential of ML in identifying frailty remains underexplored. METHODS: The study will enroll older adults wit...
The high structural similarity of antibiotics and interference from complex environmental matrices significantly hinder the precise identification and...
The rapid growth of RNA therapeutics and artificial intelligence (AI) has transformed antiviral drug discovery and created an urgent need for interdis...
Purpose To investigate whether deep learning models trained on chest radiographs (CXRs) rely on radiographic exposure parameters as shortcut features ...
INTRODUCTION: Cellular senescence, involving cell-cycle arrest and inflammatory factor release, may play a role in Long COVID development. We investig...
Neurodegenerative diseases (NDDs) are multifactorial disorders with increasing evidence implicating viral infections in their pathogenesis. However, c...
MOTIVATION: Identifying robust microbial biomarkers is crucial for disease diagnosis and prediction, elucidation of biological mechanisms, and develop...
BACKGROUND: Enterovirus infections cause substantial pediatric morbidity worldwide, with severe cases requiring hospitalization. Accurate forecasting ...
Antibody-mediated immunity directed against Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is an important immune mechanism for protect...
Antimicrobial-resistant bacterial and fungal pathogens constitute a severe threat to public health. The pace at which new antimicrobials are being rel...
Other infectious diarrhea (OID) is a major public health burden in China and a typical weather-sensitive disease, yet nationwide evidence that links c...
Bacterial swarming on a semi-solid agar surface is a prevalent form of collective motility. Our study focuses on probing the swarm front of a novel sp...
ETHNOPHARMACOLOGICAL RELEVANCE: Artemisiae Scopariae Herba (ASH) is traditionally used to treat cholestatic liver diseases and exhibits anti-tumour po...
The development of plasmonic electrochemical biosensors using the new generation of deep learning algorithms is a potent pathway toward the troublesom...
Neuroinflammation is common in people with HIV (PWH) and may be reflected also in plasma biomarkers; the latter are sometimes used as surrogates for C...
Cough is a common and physiologically informative component of respiratory morbidity, but its potential for diagnosing and monitoring disease is not t...
Efficient and accurate identification of functional genes is critical to biological research, yet traditional single-species approaches are often limi...
BACKGROUND: Chikungunya fever (CHIKF) and dengue fever are mosquito-borne viral diseases. These infections often circulate in the same regions at the ...
BACKGROUND: Robust forecasting of hepatitis B trends is important for long-term surveillance and public health planning in China. However, evidence re...