Infectious Disease

Latest AI and machine learning research in infectious disease for healthcare professionals.

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An ontology-driven clinical decision support system (IDDAP) for infectious disease diagnosis and antibiotic prescription.

BACKGROUND: The available antibiotic decision-making systems were developed from a physician's perspective. However, because infectious diseases are common, many patients desire access to knowledge via a search engine. Although the use of antibiotics should, in principle, be subject to a doctor's advice, many patients take them without authorization, and some people cannot easily or rapidly consul...

Feb 9 2018 29433958

A review of influenza detection and prediction through social networking sites.

Early prediction of seasonal epidemics such as influenza may reduce their impact in daily lives. Nowadays, the web can be used for surveillance of diseases. Search engines and social networking sites can be used to track trends of different diseases seven to ten days faster than government agencies such as Center of Disease Control and Prevention (CDC). CDC uses the Illness-Like Influenza Surveill...

Feb 1 2018 29386017
Machine learning prioritizes synthesis of primaquine ureidoamides with high antimalarial activity and attenuated cytotoxicity.

Primaquine (PQ) is a commonly used drug that can prevent the transmission of Plasmodium falciparum malaria, however toxicity limits its use. We prepar...

Jan 31 2018 29407988
Prediction of Multidrug-Resistant TB from CT Pulmonary Images Based on Deep Learning Techniques.

While tuberculosis (TB) disease was discovered more than a century ago, it has not been eradicated yet. Quite contrary, at present, TB constitutes one...

Jan 29 2018 29257894
Dew point temperature affects ascospore release of allergenic genus Leptosphaeria.

The genus Leptosphaeria contains numerous fungi that cause the symptoms of asthma and also parasitize wild and crop plants. In search of a robust and ...

Jan 27 2018 29417217
Multicentre validation of a sepsis prediction algorithm using only vital sign data in the emergency department, general ward and ICU.

OBJECTIVES: We validate a machine learning-based sepsis-prediction algorithm () for the detection and prediction of three sepsis-related gold standard...

Jan 26 2018 29374661
Recurrent Neural Network Model for Constructive Peptide Design.

We present a generative long short-term memory (LSTM) recurrent neural network (RNN) for combinatorial de novo peptide design. RNN models capture patt...

Jan 22 2018 29355319
Inhalation of Bacterial Cellulose Nanofibrils Triggers an Inflammatory Response and Changes Lung Tissue Morphology of Mice.

In view of the growing industrial use of Bacterial cellulose (BC), and taking into account that it might become airborne and be inhaled after industri...

Jan 15 2018 30766657
Image analysis and machine learning for detecting malaria.

Malaria remains a major burden on global health, with roughly 200 million cases worldwide and more than 400,000 deaths per year. Besides biomedical re...

Jan 12 2018 29360430
Transcriptional Modulation of Penicillin-Binding Protein 1b, Outer Membrane Protein P2 and Efflux Pump (AcrAB-TolC) during Heat Stress Is Correlated to Enhanced Bactericidal Action of Imipenem on Non-typeable .

The purpose of the present study was to investigate the penicillin binding proteins (PBPs), drug influx and efflux modulations during heat stress and...

Jan 12 2018 29375536
Tuberculosis diagnosis support analysis for precarious health information systems.

BACKGROUND AND OBJECTIVE: Pulmonary tuberculosis is a world emergency for the World Health Organization. Techniques and new diagnosis tools are import...

Jan 11 2018 29477418
Meta-Analysis of Expression Datasets: Comparing Virus Infection and Blood-Fed Transcriptomes to Identify Markers of Virus Presence.

The mosquito (L.) is vector of several arboviruses including dengue, yellow fever, chikungunya, and more recently zika. Previous transcriptomic studi...

Jan 11 2018 29376049
Preliminary investigation of human exhaled breath for tuberculosis diagnosis by multidimensional gas chromatography - Time of flight mass spectrometry and machine learning.

Tuberculosis (TB) remains a global public health malady that claims almost 1.8 million lives annually. Diagnosis of TB represents perhaps one of the m...

Jan 4 2018 29331743
Changes in Sleep-Wake Behavior Due to Lotus () Seed and Hwang Jeong () Extracts.

We evaluated the sleep enhancement activity of the medicinal herbs valerian (), jujube (), lotus seed (), , , and baekbokryung (), which can relieve i...

Dec 31 2017 29333381
Combined Activity of Colloid Nanosilver and Essential Oil-Mechanism of Action and Biofilm Removal Activity.

The aim of this study was to investigate antimicrobial and biofilm removal potential of Zataria multiflora essential oil (ZEO) and silver nanoparticl...

Dec 31 2017 29399552
Recent trends in antimicrobial peptide prediction using machine learning techniques.

The importance to develop effective alternatives to known antibiotics due to increased microbial resistance is gaining momentum in recent years. There...

Dec 31 2017 29379261
Abundance and Species Diversity of Fungi in Rivers with Various Contaminations.

The main objective of this work was to determine the abundance and species diversity of fungi in the waters of selected rivers of Central Europe, NE P...

Dec 30 2017 29289979
New 1,5 and 2,5-disubstituted tetrazoles-dependent activity towards surface barrier of Candida albicans.

A series of novel tetrazole derivatives was synthetized using N-alkylation or Michael-type addition reactions, and screened for their fungistatic pote...

Dec 30 2017 29324336
Procalcitonin as Predictor of Bacterial Infection in Meconium Aspiration Syndrome.

BACKGROUND: There is a lack of definite consensus on indications for initiating antibiotics in neonates with meconium aspiration syndrome (MAS), insti...

Dec 29 2017 29287292
Biosynthesis of copper nanoparticles using Shewanella loihica PV-4 with antibacterial activity: Novel approach and mechanisms investigation.

Metallic nanoparticle based disinfection represents a promising approach for microbial pollution control in drinking water and thus, biosynthesis of n...

Dec 29 2017 29304452
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