Transplantation

Liver Transplantation

Latest AI and machine learning research in liver transplantation for healthcare professionals.

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Noninvasive Evaluation of Liver Fibrosis Reverse Using Artificial Neural Network Model for Chronic Hepatitis B Patients.

The diagnostic performance of an artificial neural network model for chronic HBV-induced liver fibrosis reverse is not well established. Our research aims to construct an ANN model for estimating noninvasive predictors of fibrosis reverse in chronic HBV patients after regular antiviral therapy. In our study, 141 consecutive patients requiring liver biopsy at baseline and 1.5 years were enrolled. S...

Jul 21 2019 31428186

Optical screening of hepatitis-B infected blood sera using optical technique and neural network classifier.

In this study we demonstrate the analysis of biochemical changes in the human blood sera infected with Hepatitis B virus (HBV) using Raman spectroscopy. In total, 120 diseased blood samples and 170 healthy blood samples, collected from Pakistan Atomic Energy Commission (PAEC) general hospital, were analyzed. Spectra from each sample of both groups were collected in the spectral range 400-1700 cm. ...

Jul 9 2019 31299391
Utilizing hybrid functional fuzzy wavelet neural networks with a teaching learning-based optimization algorithm for medical disease diagnosis.

Accurate medical disease diagnosis is considered to be an important classification problem. The main goal of the classification process is to determin...

Jul 7 2019 31356992
Accurate and cost-effective prediction of HBsAg titer in industrial scale fermentation process of recombinant Pichia pastoris by using neural network based soft sensor.

In the current work, the attempt was made to apply best-fitted artificial neural network (ANN) architecture and the respective training process for pr...

Jun 24 2019 31169323
Enhancing ontology-driven diagnostic reasoning with a symptom-dependency-aware Naïve Bayes classifier.

BACKGROUND: Ontology has attracted substantial attention from both academia and industry. Handling uncertainty reasoning is important in researching o...

Jun 13 2019 31196129
Using Machine Learning Algorithms to Predict Hepatitis B Surface Antigen Seroclearance.

Hepatitis B surface antigen (HBsAg) seroclearance during treatment is associated with a better prognosis among patients with chronic hepatitis B (CHB)...

Jun 11 2019 31281411
Explant liver evaluation decodes the mystery of cryptogenic cirrhosis!

BACKGROUND AND AIM: To determine the concordance of liver explants with the pretransplant diagnosis.

May 30 2019 32055695
Streptococcus Gallolyticus endocarditis in patient with liver cirrhosis: a case report.

Streptococcus gallolyticus (S. gallolyticus) bacteremia is commonly associated with endocarditis and diseases of gastrointestinal tract, especially wi...

Apr 30 2019 32045381
LeukocyteMask: An automated localization and segmentation method for leukocyte in blood smear images using deep neural networks.

Digital pathology and microscope image analysis is widely used in comprehensive studies of cell morphology. Identification and analysis of leukocytes ...

Apr 10 2019 30891934
Booster immunity - diagnosis of chronic hepatitis B viral infection.

INTRODUCTION: Diagnosis of chronic hepatitis B virus (HBV) infection particularly its occult form requires monitoring and repeat serological and molec...

Mar 31 2019 32040457
Application of recurrent neural network for online prediction of cell density of recombinant Pichia pastoris producing HBsAg.

Artificial neural networking (ANN) seems to be a promising soft sensor for implementing current approaches of quality by design (QbD) and process anal...

Feb 1 2019 30707051
Hepatitis Screening and Treatment Campaign in Malaysia-Validation of Low-cost Point of Care Screening Tests and Nucleic Acid Tests for Hepatitis B and C.

BACKGROUND: Two major challenges in implementing budget-constrained Hepatitis screening and treatment campaign in Malaysia are the availability of low...

Feb 1 2019 30828549
Machine Learning-based Development and Validation of a Scoring System for Screening High-Risk Esophageal Varices.

BACKGROUND & AIMS: Many patients with cirrhosis who undergo esophagogastroduodenoscopy (EGD) screening for esophageal varices (EVs) are found to have ...

Jan 29 2019 30708109
Machine learning models to predict disease progression among veterans with hepatitis C virus.

BACKGROUND: Machine learning (ML) algorithms provide effective ways to build prediction models using longitudinal information given their capacity to ...

Jan 4 2019 30608929
Treatment With Grazoprevir/Elbasvir for Renal Transplant Recipients With Chronic Hepatitis C Virus Infection and Impaired Allograft Function.

BACKGROUND: Direct-acing antiviral agents are highly efficient treatment options for chronic hepatitis C virus (HCV) infection after renal allograft t...

Dec 27 2018 30656217
Data-driven supervised learning of a viral protease specificity landscape from deep sequencing and molecular simulations.

Biophysical interactions between proteins and peptides are key determinants of molecular recognition specificity landscapes. However, an understanding...

Dec 26 2018 30587591
Extracellular Vesicles from Amnion-Derived Mesenchymal Stem Cells Ameliorate Hepatic Inflammation and Fibrosis in Rats.

BACKGROUND: There are no approved drug treatments for liver fibrosis and nonalcoholic steatohepatitis (NASH), an advanced stage of fibrosis which has ...

Dec 24 2018 30675167
Retrospective Data Analysis of the Influence of Age and Sex on TPMT Activity and Its Phenotype-Genotype Correlation.

BACKGROUND: Therapeutic efficacy and toxicity of thiopurine drugs (used as anticancer and immunosuppressant agents) are affected by thiopurine S-methy...

Dec 20 2018 31639757
Acute Retroviral Syndrome Presenting as Acute Hepatitis.

Acute retroviral syndrome (ARS) can present as a wide array of clinical manifestations. Establishing a diagnosis early in the disease course can provi...

Dec 20 2018 30820375
Elevated α-Fetoprotein in the Absence of Carcinoma Caused by Relapse of Hepatitis C Viral Infection after Liver Transplantation.

We report a rare case of marked elevation of α-fetoprotein in the absence of hepatocellular carcinoma caused by a relapse of hepatitis C virus (HCV) i...

Dec 19 2018 30643846
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