Rheumatology

Lupus

Latest AI and machine learning research in lupus for healthcare professionals.

1,738 articles
Stay Ahead - Weekly Lupus research updates
Subscribe
Browse Categories
Showing 1161-1180 of 1,738 articles

Identifying multi-functional bioactive peptide functions using multi-label deep learning.

The bioactive peptide has wide functions, such as lowering blood glucose levels and reducing inflammation. Meanwhile, computational methods such as machine learning are becoming more and more important for peptide functions prediction. Most of the previous studies concentrate on the single-functional bioactive peptides prediction. However, the number of multi-functional peptides is on the increase...

Jan 17 2022 34651655

Computational anti-COVID-19 drug design: progress and challenges.

Vaccines have made gratifying progress in preventing the 2019 coronavirus disease (COVID-19) pandemic. However, the emergence of variants, especially the latest delta variant, has brought considerable challenges to human health. Hence, the development of robust therapeutic approaches, such as anti-COVID-19 drug design, could aid in managing the pandemic more efficiently. Some drug design strategie...

Jan 17 2022 34850817
Heavy chain sequence-based classifier for the specificity of human antibodies.

Antibodies specifically bind to antigens and are an essential part of the immune system. Hence, antibodies are powerful tools in research and diagnost...

Jan 17 2022 34953464
Machine Learning Prediction of Antimicrobial Peptides.

Antibiotic resistance constitutes a global threat and could lead to a future pandemic. One strategy is to develop a new generation of antimicrobials. ...

Jan 1 2022 35298806
Artificial intelligence and machine learning methods in predicting anti-cancer drug combination effects.

Drug combinations have exhibited promising therapeutic effects in treating cancer patients with less toxicity and adverse side effects. However, it is...

Nov 5 2021 34347041
Large-scale comparative review and assessment of computational methods for anti-cancer peptide identification.

Anti-cancer peptides (ACPs) are known as potential therapeutics for cancer. Due to their unique ability to target cancer cells without affecting healt...

Jul 20 2021 33316035
Unveiling the immune infiltrate modulation in cancer and response to immunotherapy by MIXTURE-an enhanced deconvolution method.

The accurate quantification of tumor-infiltrating immune cells turns crucial to uncover their role in tumor immune escape, to determine patient progno...

Jul 20 2021 33320931
A convolutional neural network algorithm for breast tumor detection with magnetic detection electrical impedance tomography.

Breast cancer is a malignant tumor disease for which early detection, diagnosis, and treatment are of paramount significance in prolonging the life of...

Jun 1 2021 34243519
Dr AFC: drug repositioning through anti-fibrosis characteristic.

Fibrosis is a key component in the pathogenic mechanism of a variety of diseases. These diseases involving fibrosis may share common mechanisms and th...

May 20 2021 32572450
Machine learning approaches for elucidating the biological effects of natural products.

Covering: 2000 to 2020 Machine learning (ML) is an efficient tool for the prediction of bioactivity and the study of structure-activity relationships....

Mar 4 2021 32869826
Unexpected Inequality: Disparate-Impact From Artificial Intelligence in Healthcare Decisions.

Systemic discrimination in healthcare plagues marginalized groups. Physicians incorrectly view people of color as having high pain tolerance, leading ...

Jan 1 2021 34185974
A Case of Dapsone-induced Mild Methemoglobinemia with Dyspnea and Cyanosis.

Dear Editor, Dapsone is a dual-function drug with antimicrobial and antiprotozoal effects and anti-inflammatory features (1). In dermatology, it is a ...

Dec 1 2020 33835002
[High-efficiency separation and analysis of monosaccharides in Pueraria polysaccharides by pressurized capillary electrochromatography].

Pueraria polysaccharides have been proven to possess biological activities such as bacteriostasis, anti-oxidative, anti-tumor, and immunity boosting a...

Nov 8 2020 34213104
Investigation of the biochemical and apoptotic changes in breast cancer cells treated with leaf extract from tea (Camellia sinensis L.) grown with added boric acid.

Tea obtained from the leaves of Camellia sinensis L., a medicinal plant, is a widely popular beverage. Deficiency in boron, a micronutrient for C. sin...

Sep 1 2020 33824097
Investigating the anti-angiogenic effects of Fufang Kushen Injection in combination with cisplatin using a zebrafish model.

The Traditional Chinese Medicine formula Fufang Kushen Injection (FKI) has demonstrated potential to enhance the efficacy and reduce the toxicity of t...

Sep 1 2020 33824101
Anti-inflammatory and antibacterial activities of P. petiolosa (Christ) Ching ethyl acetate extract against S. aureus in mice.

P. petiolosa as a typical Chinese herbal medicine has been generally utilized as Chinese native medicine formulation for treatment of chronic bronchit...

Sep 1 2020 33824112
The anti-ageing effects of a natural peptide discovered by artificial intelligence.

OBJECTIVE: As skin ages, impaired extracellular matrix (ECM) protein synthesis and increased action of degradative enzymes manifest as atrophy, wrinkl...

Aug 1 2020 32453870
A Preliminary Study of Predicting Effectiveness of Anti-VEGF Injection Using OCT Images Based on Deep Learning.

Deep learning based radiomics have made great progress such as CNN based diagnosis and U-Net based segmentation. However, the prediction of drug effec...

Jul 1 2020 33019208
Machine learning predicts new anti-CRISPR proteins.

The increasing use of CRISPR-Cas9 in medicine, agriculture, and synthetic biology has accelerated the drive to discover new CRISPR-Cas inhibitors as p...

May 21 2020 32286628
iATP: A Sequence Based Method for Identifying Anti-tubercular Peptides.

BACKGROUND: Tuberculosis is one of the biggest threats to human health. Recent studies have demonstrated that anti-tubercular peptides are promising c...

Jan 1 2020 31339073
Browse Categories