Oncology/Hematology

Other Cancers

Latest AI and machine learning research in other cancers for healthcare professionals.

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A combi-elasto ultrasound based deep learning model on liver fibrosis staging for suspected MASLD/MASH patients.

OBJECTIVES: Metabolic dysfunction-associated steatotic liver disease (MASLD) and metabolic dysfunction-associated steatohepatitis (MASH) weakened the diagnostic ability of traditional elastography ultrasound on liver fibrosis. Combi-elasto ultrasound can simultaneously reflect the information of fibrosis degree and fat accumulation, thus have better potential and generality for liver fibrosis. We ...

Jul 18 2026 42471585

Tumor cells escape from therapy-induced senescence: from molecular mechanisms to targeted intervention.

Tumor recurrence represents a significant challenge in the field of tumor therapy, severely affecting patients' survival rates and quality of life. Even after standard treatments, many patients still experience tumor recurrence. Traditional radiotherapy, chemotherapy, and targeted therapies can induce tumor cell senescence to suppress tumor growth and dissemination. However, recent studies have sh...

Jul 18 2026 42471685
Hypoxia tumor-associated macrophages facilitate hepatocellular carcinoma metastasis via uPA-uPAR pathway.

BACKGROUND: Hepatocellular carcinoma (HCC) arises within a hypoxic and immunosuppressive tumor microenvironment (TME), where tumor-associated macropha...

Jul 18 2026 42471734
Habitat-based imaging and peritumoral radiomics on ultrasound images for predicting lymphovascular invasion in breast invasive ductal carcinoma: a two-center study.

PURPOSE: This study aimed to evaluate the feasibility of employing habitat-based radiomic distributions in ultrasound (US) images to quantitatively ch...

Jul 18 2026 42471743
Circulating NSUN6 serves as a prognostic biomarker for early metastasis in HCC via hippo pathway modulation.

BACKGROUND: Portal vein tumor thrombus is a lethal complication of HCC for which effective biomarkers are urgently needed. METHODS: Through proteomic ...

Jul 17 2026 42464346
The evolving bioinformatic approaches to identifying genetic targets of promise in cancers.

INTRODUCTION: The search for actionable genetic targets in cancer has evolved substantially over the past decade. Earlier approaches were focused on s...

Jul 17 2026 42464692
Prediction of Central Lymph Node Metastasis in Papillary Thyroid Carcinoma Using Multi-Ultrasound Radiomics of Intratumoral and Peritumoral Regions.

OBJECTIVE: The aim of this study was to integrate multimodal intratumoral and peritumoral ultrasound radiomic features with clinical data to construct...

Jul 17 2026 42467019
Deep learning-based automated assessment of alveolar bone loss in CBCT for periodontitis.

OBJECTIVES: This study aimed to develop and validate a CBCT-based automated system for assessing radiographic alveolar bone loss (RBL) to improve the ...

Jul 17 2026 42467296
Is adenosine signalling entering the precision medicine era? From receptor pharmacology to patient stratification.

Over the past three decades, adenosine signalling has emerged as a fundamental regulatory system controlling immune responses, tissue homeostasis, met...

Jul 17 2026 42467297
Metabolic signatures of triple-negative breast cancer.

Triple-negative breast cancer (TNBC), being one of the most aggressive subtypes of breast malignancies, is characterized by poor prognosis and limited...

Jul 17 2026 42467335
Deep learning reveals FLAD1-mediated mitochondrial metabolic reprogramming in hypoxic tumors.

Hypoxia, a hallmark of solid tumors, drives malignant progression and represents a major therapeutic challenge. Metabolic reprogramming induced by hyp...

Jul 17 2026 42467529
Spatial architecture of tertiary lymphoid structures represents an independent prognostic dimension in hepatocellular carcinoma.

BACKGROUND AND AIMS: Tertiary lymphoid structures (TLS) are associated with heterogeneous outcomes in hepatocellular carcinoma (HCC), but whether thei...

Jul 17 2026 42468992
Multimodal Deep Fusion of Ultrasound Images and Clinical Factors for Pre-operative Prediction of Lateral Cervical Lymph Node Metastasis in Papillary Thyroid Carcinoma.

OBJECTIVE: Lateral cervical lymph node metastasis (LLNM) is missed in up to 30% of papillary thyroid carcinoma (PTC) patients pre-operatively, leading...

Jul 17 2026 42469052
Integrated bibliometric and machine learning analyses identify candidate autophagy related therapeutic targets for prostate cancer.

PURPOSE: Autophagy is increasingly recognized as a promising therapeutic target in prostate cancer (PCa), yet its research landscape has not been syst...

Jul 17 2026 42469499
Machine learning prognostication in nasopharyngeal carcinoma: a european multicentre analysis of survival and risk of second malignancy.

INTRODUCTION: Nasopharyngeal carcinoma (NPC) is rare in Europe, and emerging data suggest poorer outcomes in Caucasian patients compared with Asian po...

Jul 17 2026 42463918
Strategies to overcome barriers in access to cancer treatment in Latin America: a regional perspective.

Access to high-quality cancer care remains a major challenge across Latin America, particularly for patients with gastrointestinal (GI) malignancies. ...

Jul 16 2026 42583089
Multiomics identifies a prognostic signature and SPIB as a potential regulator of gastric cancer lymph node metastasis.

The heterogeneity within the same AJCC TNM stage of gastric cancer necessitates robust prognostic biomarkers beyond conventional staging. By integrati...

Jul 16 2026 42519041
Glycosylation-related gene risk model and functional validation of OSTC and TUBA1C in lung adenocarcinoma.

INTRODUCTION: OSTC and TUBA1C drive the malignant progression of lung adenocarcinoma (LUAD) through the modulation of N-glycosylation and the PI3K/AKT...

Jul 16 2026 42464299
A USP15/KRT17-associated 13-gene prognostic cluster and functional validation in EGFR-mutant lung adenocarcinoma.

BACKGROUND: EGFR-mutant lung adenocarcinoma (LUAD) exhibits significant prognostic heterogeneity despite the efficacy of tyrosine kinase inhibitors. T...

Jul 16 2026 42458519
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