Infectious Disease

Public Health

Latest AI and machine learning research in public health for healthcare professionals.

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Large Language Model-assisted text mining reveals bacterial pathogen diversity

Compiling and characterising the diversity of bacterial pathogens of humans is a critical challenge ...

SIMPLICITY: an agent-based, multi-scale mathematical model to study SARS-CoV-2 intra- and between-host evolution

Computational tools are frequently used to describe pathogen evolutionary dynamics either within inf...

Novel Computational Pipeline to Identify Target Sites for Broad Spectrum Antiviral Drugs

Emerging viruses pose an ongoing threat to human health. While certain viral families are common sou...

Language models learn to represent antigenic properties of human influenza A(H3) virus

Given that influenza vaccine effectiveness depends on a good antigenic match between the vaccine and...

CoV-UniBind: A Unified Antibody Binding Database for SARS-CoV-2

Since the emergence of SARS-CoV-2, numerous studies have investigated antibody interactions with vir...

WaveSeekerNet: Accurate Prediction of Influenza A Virus Subtypes and Host Source Using Attention-Based Deep Learning

Influenza A virus (IAV) poses a significant threat to animal health globally, with its ability to ov...

Mapping antigenic evolution of influenza A virus using deep learning-based prediction of hemagglutination inhibition titers

Seasonal influenza remains a significant public health challenge through unpredictable antigenic dri...

Reengineering the antigen optimization process for superior neoantigen vaccine design

Identifying effective neoantigen sequences is essential for enhancing anti-tumor immunity. However, ...

From sequence to scaffold: computational design of protein nanoparticle vaccines from AlphaFold2-predicted building blocks

Self-assembling protein nanoparticles are being increasingly utilized in the design of next-generati...

APDeeM: A machine Learning strategy towards Effective Peptide Vaccine Candidates Identification against Different Types of Viruses

Viral infections pose significant global health challenges, underscoring the urgent need for improve...

Decoding the interconnected splicing patterns of hepatitis B virus and host using large language and deep learning models

Hepatitis B virus (HBV) infection causes approximately one million deaths annually and remains a maj...

A structure-informed evolutionary model for predicting viral immune escape and evolution

Persistent emergence of viral variants capable of evading host immunity constitutes a significant th...

Influ-BERT: A Domain-Adaptive Genomic Language Model for Advancing Influenza A Virus Research

Influenza A Virus (IAV) poses a persistent threat to global public health due to its broad host adap...

Fourier transform infrared spectroscopy enables rapid species discrimination across Malassezia and strain-level typing in M. pachydermatis

Malassezia pachydermatis is a zoophilic yeast found on the skin and in the outer ear canal of many m...

T-SCAPE: T-cell Immunogenicity Scoring via Cross-domain Aided Predictive Engine

T-cell immunogenicity, the ability of peptide fragments to elicit T-cell responses, is a critical de...

Mapping Risk and Conservation Potential Across the Indo-Pacific with Reefshark Genomescapes

Overfishing has severely depleted marine populations worldwide, including within protected areas. Il...

Machine Learning Enables Viral Genome-Agnostic Classification of RNA Virus Infections from Host Transcriptomes

Targeted PCR diagnosis of RNA viruses is sequence dependent, meaning that the accuracy of the assay ...

Species-agnostic and Salmonella-specific Models for Antimicrobial Resistance Prediction Using FCGR and ResNet-18

Antimicrobial resistance (AMR) prediction from bacterial genomes remains a major challenge for clini...

Recovery of human upper airway epithelium after smoking cessation is driven by a slow-cycling stem cell population and immune surveillance

The upper airway epithelium in humans is maintained in homeostasis by a resident population of basal...

Hollow-fibre biomanufacturing and cell-free engineering of HEK293 extracellular vesicles

Extracellular vesicles (EVs) are lipid-delineated nanoparticles that are produced by most cell types...

Machine learning based lineage prediction from AMR phenotypes for Escherichia coli ST131 clade C surveillance across infection types

Rising antimicrobial resistance (AMR) in Escherichia coli bloodstream infections (BSIs) in high-inco...

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