Latest AI and machine learning research in rheumatology for healthcare professionals.
The present study demonstrates apoptosis-inducing potential and mechanism of action of alkaloid extract in Jurkat E6-1 cancer cell line. Liquid Chromatography-Mass Spectrometry and High Resolution-Mass Spectrometry analysis identified the presence of four -feruloyltyramine derivatives, namely trans--feruloyl-3-hydroxytyramine (), trans--coumaroyltyramine (), trans--feruloyltyramine () and trans--...
Melanoma is the deadliest type of skin cancer. CD20+ melanoma stem cells (CSCs) are pivotal for metastasis and initiation of melanoma. Therefore, selective elimination of CD20+ melanoma CSCs represents an effective treatment to eradicate melanoma. Salinomycin has emerged as an effective drug toward various CSCs. Due to its poor solubility, its therapeutic efficacy against melanoma CSCs has never b...
As the mechanism of aged black garlic (ABG) extract affecting lipid metabolism in adipocytes remains unclear, this study evaluated the effect of ABG e...
Direct-acting antiviral agents (DAAs) represent the major advance in hepatitis C virus (HCV) infection treatment leading to extremely high eradication...
This study aims to evaluate the cytotoxic and anti-migratory effects of L. on prostate cancer cells, identify the active compound/s and characterize...
Herbs have played a fundamental and essential role in the humans life since ancient times, especially those which are used as food and/or folk medici...
This work investigated the preparation of chitosan nanoparticles used as carriers for doxorubicin for targeted cancer delivery. Prepared nanocarriers ...
A new strain, namely sp. BV152.1 was isolated from the rhizosphere of ground ivy ( L.) producing metabolites with potent ability to inhibit biofilm f...
The angiotensin-(1-7)/angiotensin-converting enzyme 2/Mas receptor axis counter-regulates the detrimental effects of angiotensin II. Beneficial effec...
This paper describes an analysis of the diversity and chemical toxicity assessment of three chemical libraries of compounds from African flora (the p-...
Serum soluble interleukin-2 receptor (sIL-2r) is an important disease marker in hemophagocytic lymphohistiocytosis (HLH), but there are no published d...
For the past decades, there has been a growing demand for natural antimicrobials in the food industry. Plant extracts have attracted strong research i...
BACKGROUND: Severe immune dysregulation such as seen in autoimmune (AI) disease is known to act as a significant risk factor for diffuse large B-cell ...
Investigations of anti-HIV-1 human hematopoietic stem/progenitor cell (HSPC)-based gene therapy have been performed by HIV-1 challenge after the engra...
Ultrasound is widely used in the diagnosis and follow-up of chronic arthritis. We present an evaluation of a novel automatic ultrasound diagnostic too...
The present study was aimed to explore the anti-venom activity of Aristolochia indica and Piper nigrum plants against the centipede (Scolopendra moris...
First-line anti-tuberculosis drugs are playing vital roles for curbing rapid spread of tuberculosis. Multidrug therapies are commonly applied in clini...
The purpose of this study was to investigate the applicability of green tea seed (GTS) extract as a natural preservative in food. Food preservative ab...
To determine the degree of cancer cell killing after treatment with chemotherapeutic drugs, we have developed a sensitive platform using localized sur...
BACKGROUND: Arthritis is the leading cause of work disability and contributes to lost productivity. Previous studies showed that various factors predi...