Latest AI and machine learning research in stem cell research for healthcare professionals.
INTRODUCTION: Proton pump inhibitors (PPIs) are widely used to treat acid-related disorders; however, treatment response varies significantly due to Cytochrome P450 2C19 (CYP2C19) genetic polymorphisms that alter individual drug metabolism. Such variation can lead to insufficient acid suppression, resulting in treatment failure or adverse events. Genotype-guided PPI therapy represents an important...
BACKGROUND: Evidence indicates that artificial intelligence (AI) can improve mammography screening by increasing cancer detection and reducing screen reading workload, but its effect on interval cancers (primary breast cancers diagnosed between two screening rounds or within 2 years after the last scheduled screening that were not detected at screening) is unknown. We aimed to compare the interval...
BACKGROUND: Accurate assessment of mortality, bleeding, and atherothrombotic risk in patients with cancer and acute coronary syndrome could inform nov...
Cancer arises and is resistant to therapy via intricate molecular networks that are poorly characterised. While individually, Cullin-3 (CUL3) and circ...
Resistance to lenvatinib has become a major obstacle in the clinical treatment of liver cancer, highlighting the significant research value and transl...
Neoadjuvant therapy is a cornerstone of modern oncology, yet its efficacy is traditionally assessed only after treatment completion, creating a "black...
BACKGROUND: Management of amyotrophic lateral sclerosis (ALS) is complicated by heterogeneous presentation and unpredictable disease course. This stud...
BACKGROUND: The glymphatic system plays a critical role in brain waste clearance and health. Diffusion tensor imaging along the perivascular space (DT...
BACKGROUND: Pharmacotyping, the ex vivo measurement of tumor cell responses to drugs, is particularly important for cancers lacking actionable genomic...
BACKGROUND: Trauma is a major global cause of morbidity and mortality, with haemorrhage representing a leading preventable cause of early death. Timel...
Rectal cancer management has increasingly shifted toward organ-preserving strategies that aim to maintain oncologic control while preserving bowel, ur...
Lung adenocarcinoma (LUAD) displays significant morphological and molecular heterogeneity both within and between tumors. This heterogeneity, coupled ...
OBJECTIVES: Digital technology in primary healthcare service delivery can enhance accessibility, service delivery and health outcomes in rural populat...
BACKGROUND: Early detection of cardiovascular disease is a global public health priority. Artificial intelligence (AI)-enabled stethoscopes offer robu...
Aging and age-related diseases are a major public health concern, driving interest in anti-aging research. While small molecules and natural compounds...
Immunotherapy, a therapeutic strategy aimed at modulating the host immune system, has undergone rapid evolution over recent decades, particularly in o...
BACKGROUND: As artificial intelligence (AI) becomes increasingly embedded in clinical decision-making and preventive care, it is urgent to address eth...
Biological proteins play a crucial role at the intersection of oral health and neuroscience, offering promising opportunities for improved diagnosis, ...
Across health care, traditional principles of biomedical ethics (autonomy, beneficence, nonmaleficence, and justice) form a base expectation for the u...
Mechanoresponsive biomaterials are a revolutionary class of materials designed to respond dynamically to mechanical stimuli, providing tissue engineer...