Urology

Latest AI and machine learning research in urology for healthcare professionals.

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Integrating Cascade Mechanistic Insights into Structure-Activity Relationships for Quantitative Mode-of-Action Analysis: A Novel Risk Assessment Framework for OPFRs.

Organophosphate flame retardants (OPFRs), as emerging substitutes for halogenated flame retardants, are widely detected in populations and pose global health concerns. However, their structural diversity and expanding numbers challenge conventional experimental risk assessment. Here, we present a quantitative mode-of-action (qMOA) framework integrating structural attributes and cascade mechanistic...

Apr 19 2026 42003089

Self-Supervised Deep Learning Framework for Rician Distribution Based Denoising and Modeling of Multi-b Prostate Diffusion MRI.

PURPOSE: Convolutional neural networks (CNNs) are evaluated for improved and accelerated denoising and Rician bias correction in multi-b DW images with simultaneous signal modeling. METHODS: Prostate diffusion images from 46 individuals acquired at 20 linearly distributed b-values ( b max = 2000 s / mm 2 ) $$ {b}_{\mathrm{max}}=2000\kern0.3em \mathrm{s}/{\mathrm{mm}}^2\Big) $$ without avera...

Apr 19 2026 42003179
Integrated multi-omics data and machine learning approaches to decipher the molecular network and gene signatures of renal cell carcinoma induced by aristolochic acid.

OBJECTIVE: This study aims to delineate the molecular mechanisms through which aristolochic acid (AA) exposure drives renal cell carcinoma (RCC) patho...

Apr 18 2026 42033937
Integrated multi-omics and machine learning highlight PTM-related genes as potential biomarkers in endometrial cancer.

BACKGROUND: Endometrial cancer, the most common gynecological malignancy, represents about 5 % of all cancers in women, with rising incidence rates. E...

Apr 18 2026 42001686
Development and Validation of Machine Learning Models to Identify Emergency Department Patients at Increased Risk of New or Progressive Acute Kidney Injury.

OBJECTIVES: Acute kidney injury (AKI) is a common and serious condition associated with prolonged hospitalization, chronic kidney disease, and increas...

Apr 18 2026 42016808
Circulating Neutrophils Exhibit an Altered Immune Response in Chronic LUTS: An Image-Based Deep Learning Analysis.

INTRODUCTION AND HYPOTHESIS: Chronic lower urinary tract symptoms (LUTS) are characterised by persistent symptoms and elevated urinary leukocyte count...

Apr 18 2026 41999502
Interactive multimodal disease risk evaluation using a self-service non-invasive device.

BACKGROUND: Non-communicable diseases such as diabetes, fatty liver disease and chronic kidney disease are major global health burdens that benefit fr...

Apr 18 2026 42000886
A noninvasive urinary microRNA-based assay for early detection of lung cancer and its potential application to prognosis and recurrence monitoring: a case-control study.

Lung cancer remains the leading cause of cancer-related mortality worldwide, with recurrence or cancer-related death occurring even after curative-int...

Apr 18 2026 42000891
[Current status and future perspectives of precision treatment for locally advanced rectal cancer].

The treatment paradigm for locally advanced rectal cancer is undergoing a fundamental transformation from the traditional fixed triad of "radiotherapy...

Apr 18 2026 41978391
Investigation of the use of urinary proteomics in the prediction of childhood asthma.

PURPOSE: Urinary proteomics may help us improve our understanding and classification of asthma. We sought to identify clusters of children based on ur...

Apr 17 2026 42001975
Novel therapeutic strategies for metastatic castration‑resistant prostate cancer: Beyond androgen receptor pathway inhibition (Review).

Metastatic castration‑resistant prostate cancer (mCRPC) remains a lethal disease due to universal resistance to androgen‑receptor pathway inhibitors (...

Apr 17 2026 41992975
Application of an open-source AI tool for quantitative quality control in whole slide images of prostate needle core biopsies - a retrospective study.

The quality of Whole Slide Images (WSI) is a determining factor for proper diagnosis and prognosis, and for enhanced performance of Digital and Comput...

Apr 17 2026 41994924
Promptable segmentation with region exploration enables minimal-effort expert-level prostate cancer delineation.

PURPOSE: Accurate segmentation of prostate cancer on magnetic resonance (MR) images is crucial for planning image-guided interventions such as targete...

Apr 17 2026 41996003
Assessment of AI-Generated Patient Education Materials for Bladder Training and Pelvic Floor Muscle Therapy: Comparison with an International Society Leaflet.

INTRODUCTION AND HYPOTHESIS: High-quality patient education materials are essential in urogynecology. We hypothesized that patient handouts generated ...

Apr 17 2026 41998329
Non-invasive diagnosis strategy integrating PSMA PET/CT and mpMRI for patients with suspected prostate cancer: a multi-center study.

BACKGROUND: Multiparametric MRI (mpMRI) and ^68 Ga-PSMA PET/CT are widely used for prostate cancer (PCa) diagnosis but remain limited by false positiv...

Apr 16 2026 41992197
Clinically Localized Prostate Cancer: AUA/ASTRO Guideline Amendment (2026).

PURPOSE: Following completion of the 2025 Update Literature Review (ULR), the American Urological Association (AUA) incorporated new evidence generate...

Apr 16 2026 41988960
DeFecT-FF: a machine learning force field framework for high throughput defect modeling in CdTe-based solar cells.

We developed a framework for predicting the energies and ground state configurations of native point defects, extrinsic dopants and impurities, and de...

Apr 16 2026 41989819
Artificial Intelligence Design for Race-Based Prostate Cancer Stage Classification With Multilayer Perceptron: Feature Selection Optimization Approach.

BACKGROUND: Prostate cancer progression exhibits significant variability influenced by biological and racial factors. DNA methylation profiling has sh...

Apr 16 2026 41989963
Molecular Biomarkers and Risk Prediction Models for Acute Kidney Injury Following Liver Transplantation: A Review.

Liver transplantation is the definitive treatment for end-stage liver disease; however, postoperative acute kidney injury (AKI) affects 30%-70% of rec...

Apr 16 2026 42165038
Radiomics Applicability Domain Analysis Classification Framework (RADAN-CF): A method for evaluating prediction reliability in radiomics.

BACKGROUND AND OBJECTIVE: Radiomics-based machine learning models hold promise for clinical decision support, yet their deployment may be limited by t...

Apr 15 2026 42001654
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