Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Aug 28, 2024
In cancer research, oncogenesis can be affected by modulating the deubiquitination pathway. Ubiquitination regulates proteins post-translationally in variety of physiological processes. The Otubain Subfamily includes OTUB1 (ovarian tumor-associated p...
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Jun 28, 2024
The integration of biochips with AI opened up new possibilities and is expected to revolutionize smart healthcare tools within the next five years. The combination of miniaturized, multi-functional, rapid, high-throughput sample processing and sensin...
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
May 6, 2024
Peptide medications have been more well-known in recent years due to their many benefits, including low side effects, high biological activity, specificity, effectiveness, and so on. Over 100 peptide medications have been introduced to the market to ...
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Apr 3, 2024
BACKGROUND: Serum transaminases, alkaline phosphatase and bilirubin are common parameters used for DILI diagnosis, classification, and prognosis. However, the relevance of clinical examination, histopathology and drug chemical properties have not bee...
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Mar 21, 2024
Ubiquitin-specific protease (USP), an enzyme catalyzing protein deubiquitination, is involved in biological processes related to metabolic disorders and cancer proliferation. We focused on constructing predictive models tailored to unveil compounds b...
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Mar 20, 2024
Parkinson's disease (PD) is a complex neurodegenerative disorder with an unclear etiology. Despite significant research efforts, developing disease-modifying treatments for PD remains a major unmet medical need. Notably, drug repositioning is becomin...
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Oct 12, 2023
Due to its high mortality rate associated with various life-threatening sequelae, meningitis poses a vital problem in contemporary medicine. Numerous algorithms, many of which were derived with the aid of artificial intelligence, were brought up in a...
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Jul 1, 2023
Traditional bulk sequencing methods are limited to measuring the average signal in a group of cells, potentially masking heterogeneity, and rare populations. The single-cell resolution, however, enhances our understanding of complex biological system...
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Apr 28, 2023
More information about a person's genetic makeup, drug response, multi-omics response, and genomic response is now available leading to a gradual shift towards personalized treatment. Additionally, the promotion of non-animal testing has fueled the c...
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
Dec 17, 2022
Large skin defects caused by accidents or disease can cause fluid loss, water and electrolyte disorders, hypoproteinemia and serious infection and remain a difficult problem in clinical practice. In situ bioprinting is a promising, recently developed...