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Cholestasis

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Robotic Revision of Hepaticojejunostomy for Benign Biliary Stricture.

The American surgeon
Surgical revision of biliary enteric anastomoses (BEA) can be a challenging undertaking and a robotic platform may provide advantages that address many of the technical obstacles. We present our technical approach and outcomes for patients undergoing...

Identification of patients with malignant biliary strictures using a cholangioscopy-based deep learning artificial intelligence (with video).

Gastrointestinal endoscopy
BACKGROUND AND AIMS: Accurately diagnosing malignant biliary strictures (MBSs) as benign or malignant remains challenging. It has been suggested that direct visualization and interpretation of cholangioscopy images provide greater accuracy for strict...

Diagnosing malignant distal bile duct obstruction using artificial intelligence based on clinical biomarkers.

Scientific reports
Diagnosing distal bile duct obstruction remains challenging. This study aimed to examine the diagnostic ability of artificial intelligence (AI) based on clinical biomarkers in diagnosing malignant distal bile duct obstruction. A total of 206 patients...

Predictive modeling for early detection of biliary atresia in infants with cholestasis: Insights from a machine learning study.

Computers in biology and medicine
Cholestasis, characterized by the obstruction of bile flow, poses a significant concern in neonates and infants. It can result in jaundice, inadequate weight gain, and liver dysfunction. However, distinguishing between biliary atresia (BA) and non-bi...

Novel clinical phenotypes, drug categorization, and outcome prediction in drug-induced cholestasis: Analysis of a database of 432 patients developed by literature review and machine learning support.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
BACKGROUND: Serum transaminases, alkaline phosphatase and bilirubin are common parameters used for DILI diagnosis, classification, and prognosis. However, the relevance of clinical examination, histopathology and drug chemical properties have not bee...

Artificial intelligence for automatic diagnosis and pleomorphic morphological characterization of malignant biliary strictures using digital cholangioscopy.

Scientific reports
Diagnosing and characterizing biliary strictures (BS) remains challenging. Artificial intelligence (AI) applied to digital single-operator cholangioscopy (D-SOC) holds promise for improving diagnostic accuracy in indeterminate BS. This multicenter st...

Leveraging machine learning for precision medicine: a predictive model for cognitive impairment in cholestasis patients.

BMC gastroenterology
BACKGROUND: Cholestasis, characterized by impaired bile flow, impacts cognitive function through systemic mechanisms, including inflammation and metabolic dysregulation. Despite its significance, targeted predictive models for cognitive impairment in...