AIMC Journal:
Journal of biomedical informatics

Showing 441 to 450 of 650 articles

Exploiting MEDLINE for gene molecular function prediction via NMF based multi-label classification.

Journal of biomedical informatics Aug 18, 2018
Gene ontology (GO) provides a representation of terms and categories used to describe genes and their molecular functions, cellular components and biological processes. GO has been the standard for describing the functions of specific genes in differ...
Models, Statistical Decision Trees Databases, Protein Predictive Value of Tests Markov Chains MEDLINE Molecular Sequence Annotation Gene Ontology Reproducibility of Results Animals Humans Computational Biology Algorithms Databases, Genetic
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A convolutional route to abbreviation disambiguation in clinical text.

Journal of biomedical informatics Aug 15, 2018
OBJECTIVE: Abbreviations sense disambiguation is a special case of word sense disambiguation. Machine learning methods based on neural networks showed promising results for word sense disambiguation (Festag and Spreckelsen, 2017) [1] and, here we ass...
Databases, Factual Language Reproducibility of Results Hospitals Neural Networks, Computer Software Algorithms Medical Informatics Automation Semantics Ohio Deep Learning Support Vector Machine Cluster Analysis Data Collection
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Risk prediction using natural language processing of electronic mental health records in an inpatient forensic psychiatry setting.

Journal of biomedical informatics Aug 14, 2018
OBJECTIVE: Instruments rating risk of harm to self and others are widely used in inpatient forensic psychiatry settings. A potential alternate or supplementary means of risk prediction is from the automated analysis of case notes in Electronic Health...
Tasmania Support Vector Machine Mental Health Services Regression Analysis Inpatients Natural Language Processing Ethics, Medical Unified Medical Language System Forensic Psychiatry Reproducibility of Results Sensitivity and Specificity Mental Health Risk Assessment Humans Algorithms Electronic Health Records
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Skin lesion classification with ensembles of deep convolutional neural networks.

Journal of biomedical informatics Aug 10, 2018
Skin cancer is a major public health problem with over 123,000 newly diagnosed cases worldwide in every year. Melanoma is the deadliest form of skin cancer, responsible for over 9000 deaths in the United States each year. Thus, reliable automatic mel...
Diagnosis, Computer-Assisted Databases, Factual Humans ROC Curve Keratosis, Seborrheic Melanoma Image Processing, Computer-Assisted Neural Networks, Computer Melanocytes Skin Neoplasms Nevus Machine Learning Dermoscopy Algorithms
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Trie-based rule processing for clinical NLP: A use-case study of n-trie, making the ConText algorithm more efficient and scalable.

Journal of biomedical informatics Aug 6, 2018
OBJECTIVE: To develop and evaluate an efficient Trie structure for large-scale, rule-based clinical natural language processing (NLP), which we call n-trie.
Algorithms Databases, Factual Computational Biology Natural Language Processing Humans Machine Learning
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Predict effective drug combination by deep belief network and ontology fingerprints.

Journal of biomedical informatics Aug 3, 2018
The synergistic effect of drug combination is one of the most desirable properties for treating cancer. However, systematically predicting effective drug combination is a significant challenge. We report here a novel method based on deep belief netwo...
Humans Neoplasms Gene Expression Profiling Deep Learning Drug Combinations Drug Synergism Gene Ontology Databases, Pharmaceutical Cell Line, Tumor Gene Regulatory Networks Computational Biology Antineoplastic Combined Chemotherapy Protocols
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An unsupervised machine learning method for discovering patient clusters based on genetic signatures.

Journal of biomedical informatics Jul 29, 2018
INTRODUCTION: Many chronic disorders have genomic etiology, disease progression, clinical presentation, and response to treatment that vary on a patient-to-patient basis. Such variability creates a need to identify characteristics within patient popu...
Unsupervised Machine Learning Gene Ontology Linkage Disequilibrium Humans Algorithms Polymorphism, Single Nucleotide Precision Medicine Computational Biology Genome-Wide Association Study Databases, Genetic Gene Regulatory Networks Cluster Analysis
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Mining features for biomedical data using clustering tree ensembles.

Journal of biomedical informatics Jul 29, 2018
The volume of biomedical data available to the machine learning community grows very rapidly. A rational question is how informative these data really are or how discriminant the features describing the data instances are. Several biomedical datasets...
Saccharomyces cerevisiae Decision Trees Humans Metabolic Networks and Pathways Data Mining Gene Regulatory Networks Computational Biology Escherichia coli Cluster Analysis Machine Learning Algorithms Databases, Factual Protein Interaction Maps
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Transferability of artificial neural networks for clinical document classification across hospitals: A case study on abnormality detection from radiology reports.

Journal of biomedical informatics Jul 17, 2018
OBJECTIVE: Application of machine learning techniques for automatic and reliable classification of clinical documents have shown promising results. However, machine learning models require abundant training data specific to each target hospital and m...
Support Vector Machine Algorithms Humans Databases, Factual Radiography Neural Networks, Computer Deep Learning Radiographic Image Interpretation, Computer-Assisted Machine Learning Computational Biology
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Classification of ADHD with bi-objective optimization.

Journal of biomedical informatics Jul 17, 2018
Attention Deficit Hyperactive Disorder (ADHD) is one of the most common diseases in school aged children. In this paper, we consider using fMRI data with classification techniques to aid the diagnosis of ADHD and propose a bi-objective ADHD classific...
Reproducibility of Results Child Image Processing, Computer-Assisted Support Vector Machine Magnetic Resonance Imaging Decision Making Models, Statistical Brain Mapping Humans Algorithms Databases, Factual Medical Informatics Attention Deficit Disorder with Hyperactivity
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