AI Medical Compendium Journal:
Molecular medicine (Cambridge, Mass.)

Showing 1 to 3 of 3 articles

Transcriptome-wide analysis reveals potential roles of CFD and ANGPTL4 in fibroblasts regulating B cell lineage for extracellular matrix-driven clustering and novel avenues for immunotherapy in breast cancer.

Molecular medicine (Cambridge, Mass.) May 8, 2025
BACKGROUND: The remodeling of the extracellular matrix (ECM) plays a pivotal role in tumor progression and drug resistance. However, the compositional patterns of ECM in breast cancer and their underlying biological functions remain elusive.
Humans Prognosis Female Breast Neoplasms Tumor Microenvironment Gene Expression Profiling Transcriptome Gene Regulatory Networks Immunotherapy Gene Expression Regulation, Neoplastic Fibroblasts B-Lymphocytes Extracellular Matrix Cell Lineage Angiopoietin-Like Protein 4
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Multi‑omics identification of a novel signature for serous ovarian carcinoma in the context of 3P medicine and based on twelve programmed cell death patterns: a multi-cohort machine learning study.

Molecular medicine (Cambridge, Mass.) Jan 8, 2025
BACKGROUND: Predictive, preventive, and personalized medicine (PPPM/3PM) is a strategy aimed at improving the prognosis of cancer, and programmed cell death (PCD) is increasingly recognized as a potential target in cancer therapy and prognosis. Howev...
Humans Machine Learning Precision Medicine Prognosis Female Biomarkers, Tumor Middle Aged Gene Expression Profiling Transcriptome Cohort Studies Genomics Computational Biology Multiomics Gene Expression Regulation, Neoplastic Apoptosis Ovarian Neoplasms Cystadenocarcinoma, Serous
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Machine learning-driven discovery of novel therapeutic targets in diabetic foot ulcers.

Molecular medicine (Cambridge, Mass.) Nov 14, 2024
BACKGROUND: To utilize machine learning for identifying treatment response genes in diabetic foot ulcers (DFU).
Humans Machine Learning Biomarkers Female Male Gene Expression Profiling Transcriptome Single-Cell Analysis Computational Biology Wound Healing Diabetic Foot Calcium-Binding Proteins
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