AI Medical Compendium Journal:
PLoS computational biology

Showing 21 to 30 of 484 articles

Reliability-enhanced data cleaning in biomedical machine learning using inductive conformal prediction.

PLoS computational biology
Accurately labeling large datasets is important for biomedical machine learning yet challenging while modern data augmentation methods may generate noise in the training data, which may deteriorate machine learning model performance. Existing approac...

Early detection of disease outbreaks and non-outbreaks using incidence data: A framework using feature-based time series classification and machine learning.

PLoS computational biology
Forecasting the occurrence and absence of novel disease outbreaks is essential for disease management, yet existing methods are often context-specific, require a long preparation time, and non-outbreak prediction remains understudied. To address this...

Mapping the learning curves of deep learning networks.

PLoS computational biology
There is an important challenge in systematically interpreting the internal representations of deep neural networks (DNNs). Existing techniques are often less effective for non-tabular tasks, or they primarily focus on qualitative, ad-hoc interpretat...

ASGCL: Adaptive Sparse Mapping-based graph contrastive learning network for cancer drug response prediction.

PLoS computational biology
Personalized cancer drug treatment is emerging as a frontier issue in modern medical research. Considering the genomic differences among cancer patients, determining the most effective drug treatment plan is a complex and crucial task. In response to...

The calcitron: A simple neuron model that implements many learning rules via the calcium control hypothesis.

PLoS computational biology
Theoretical neuroscientists and machine learning researchers have proposed a variety of learning rules to enable artificial neural networks to effectively perform both supervised and unsupervised learning tasks. It is not always clear, however, how t...

Human-like face pareidolia emerges in deep neural networks optimized for face and object recognition.

PLoS computational biology
The human visual system possesses a remarkable ability to detect and process faces across diverse contexts, including the phenomenon of face pareidolia--seeing faces in inanimate objects. Despite extensive research, it remains unclear why the visual ...

Exploiting the similarity of dissimilarities for biomedical applications and enhanced machine learning.

PLoS computational biology
The "similarity of dissimilarities" is an emerging paradigm in biomedical science with significant implications for protein function prediction, machine learning (ML), and personalized medicine. In protein function prediction, recognizing dissimilari...

The tumour histopathology "glossary" for AI developers.

PLoS computational biology
The applications of artificial intelligence (AI) and deep learning (DL) are leading to significant advances in cancer research, particularly in analysing histopathology images for prognostic and treatment-predictive insights. However, effective trans...

A robust transfer learning approach for high-dimensional linear regression to support integration of multi-source gene expression data.

PLoS computational biology
Transfer learning aims to integrate useful information from multi-source datasets to improve the learning performance of target data. This can be effectively applied in genomics when we learn the gene associations in a target tissue, and data from ot...

The role of chromatin state in intron retention: A case study in leveraging large scale deep learning models.

PLoS computational biology
Complex deep learning models trained on very large datasets have become key enabling tools for current research in natural language processing and computer vision. By providing pre-trained models that can be fine-tuned for specific applications, they...