AIMC Topic: Acetylcysteine
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Intestinal permeability of N-acetylcysteine is driven by gut microbiota-dependent cysteine palmitoylation.
Nature communications
May 19, 2025
Trillions of intestinal microbiota are essential to the permeability of orally administered drugs. However, identifying microbial-drug interactions remains challenging due to the highly variable composition of intestinal flora among individuals. Usin...
Efficacy and safety of inhaled N-acetylcysteine in idiopathic pulmonary fibrosis: A prospective, single-arm study.
Respiratory investigation
Dec 15, 2015
BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with few treatment options. The efficacy of N-acetylcysteine in patients with IPF remains controversial. The aim of this research was to investigate the efficacy of inhaled...
Cytotoxic response of platinum-coated gold nanorods in human breast cancer cells at very low exposure levels.
Environmental toxicology
Apr 6, 2015
Because of unique optical behavior gold nanorods (GNRs) have attracted attention for the application in biomedical field such as bio-sensing, bio-imaging and hyperthermia. However, toxicological response of GNRs is controversial due to their differen...
Humans
Female
Breast Neoplasms
Real-Time Polymerase Chain Reaction
RNA, Messenger
Apoptosis
Reactive Oxygen Species
Caspase 3
Particle Size
MCF-7 Cells
Gold
Membrane Potential, Mitochondrial
Platinum
Proto-Oncogene Proteins c-bcl-2
Down-Regulation
Up-Regulation
Nanotubes
Acetylcysteine
Caspase 9
G1 Phase Cell Cycle Checkpoints
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