INTRODUCTION: Aging is characterized by gradual structural and functional changes in the body over time, with intervertebral disc degeneration (IVDD) representing a key manifestation of spinal aging and a major contributor to low back pain (LBP).
Magnetic resonance Imaging (MRI)-derived brain-age prediction is a promising biomarker of biological brain aging. Accelerated brain aging has been found in Alzheimer's disease (AD) and other neurodegenerative diseases. However, no previous studies ha...
BACKGROUND: The global increase in life expectancy has not shown a similar rise in healthy life expectancy. Accurate assessment of biological aging is crucial for mitigating diseases and socioeconomic burdens associated with aging. Current biological...
Journal of plastic surgery and hand surgery
Apr 3, 2025
BACKGROUND: The quest for eternal youth has been a common theme in many cultures for centuries. While we have yet to discover a way to preserve youth eternally, we have made significant progress in understanding the aging process and in developing ph...
Recent associations between Major Depressive Disorder (MDD) and measures of premature aging suggest accelerated biological aging as a potential biomarker for MDD susceptibility or MDD as a risk factor for age-related diseases. Residuals or "gaps" bet...
Brain age gap, the difference between estimated brain age and chronological age via magnetic resonance imaging, has emerged as a pivotal biomarker in the detection of brain abnormalities. While deep learning is accurate in estimating brain age, the a...
BACKGROUND: While the Cardiometabolic Index (CMI) serves as a novel marker for assessing adipose tissue distribution and metabolic function, its prognostic utility for cardiovascular disease (CVD) events remains incompletely understood. This investig...
Adipogenesis is intricately linked to the onset and progression of muscle aging; however, the relevant biomarkers remain unclear. This study sought to identify key genes associated with adipogenesis in the context of muscle aging. Firstly, gene expre...
Magnetic resonance imaging (MRI)-derived hippocampus measurements have been associated with different cognitive domains. The knowledge of hippocampal structural deformations as we age has contributed to our understanding of the overall aging process....
BACKGROUND: Depression has a detrimental effect on an individual's mental and musculoskeletal strength multiplying the risk of fall incidents. The current study aims to investigate the association between depression and falls in older adults using ma...
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