Drug-associated adverse events cause approximately 30 billion dollars a year of added health care expense, along with negative health outcomes including patient death. This constitutes a major public health concern. The US Food and Drug Administratio...
Magnetic resonance imaging (MRI) images can be used to diagnose brain tumors. Thanks to these images, some methods have so far been proposed in order to distinguish between benign and malignant brain tumors. Many systems attempting to define these tu...
AIM: To assess the potential of supervised machine-learning techniques to identify clinical variables for predicting short-term and long-term glycated haemoglobin (HbA1c) response after insulin treatment initiation in patients with type 2 diabetes me...
Real-time simulation of bio-heat transfer can improve surgical feedback in thermo-therapeutic treatment, leading to technical innovations to surgical process and improvements to patient outcomes; however, it is challenging to achieve real-time comput...
International journal of molecular sciences
Sep 30, 2019
The constitutive androstane receptor (CAR) plays pivotal roles in drug-induced liver injury through the transcriptional regulation of drug-metabolizing enzymes and transporters. Thus, identifying regulatory factors for CAR activation is important for...
What is the physiological basis of long-term memory? The prevailing view in Neuroscience attributes changes in synaptic efficacy to memory acquisition, implying that stable memories correspond to stable connectivity patterns. However, an increasing b...
Cancer driver genes, i.e., oncogenes and tumor suppressor genes, are involved in the acquisition of important functions in tumors, providing a selective growth advantage, allowing uncontrolled proliferation and avoiding apoptosis. It is therefore imp...
Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI)
Sep 29, 2019
BACKGROUND: The visual assessment and severity grading of acne vulgaris by physicians can be subjective, resulting in inter- and intra-observer variability.
Computer methods and programs in biomedicine
Sep 27, 2019
BACKGROUND AND OBJECTIVES: The retinal fundus contains intricate vascular trees, some of which are mutually intersected and overlapped. The intersection and overlapping of retinal vessels represent vascular junctions (i.e. bifurcation and crossover) ...
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