AIMC Topic: Algorithms

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Gene Expression Data Based Deep Learning Model for Accurate Prediction of Drug-Induced Liver Injury in Advance.

Journal of chemical information and modeling
Drug-induced liver injury (DILI), one of the most common adverse effects, leads to drug development failure or withdrawal from the market in most cases, showing an emerging challenge that is to accurately predict DILI in the early stage. Recently, th...

Respiratory Sound Based Classification of Chronic Obstructive Pulmonary Disease: a Risk Stratification Approach in Machine Learning Paradigm.

Journal of medical systems
This article investigates the classification of normal and COPD subjects on the basis of respiratory sound analysis using machine learning techniques. Thirty COPD and 25 healthy subject data are recorded. Total of 39 lung sound features and 3 spirome...

A Machine Learning-Based Approach for the Prediction of Acute Coronary Syndrome Requiring Revascularization.

Journal of medical systems
The aim of this study is to predict acute coronary syndrome (ACS) requiring revascularization in those patients presenting early-stage angina-like symptom using machine learning algorithms. We obtained data from 2344 ACS patients, who required revasc...

Determination of the physical domain for air quality monitoring stations using the ANP-OWA method in GIS.

Environmental monitoring and assessment
Air pollution is a major concern in some megacities of Iran. Specific cities in the country have reached an extremely harmful level of air pollution which poses a serious risk to the daily lives of Iranians. According to news reports, the air quality...

Using machine learning to understand the temporal morphology of the PM annual cycle in East Asia.

Environmental monitoring and assessment
PM air pollution is a significant issue for human health all over the world, especially in East Asia. A large number of ground-based measurement sites have been established over the last decade to monitor real-time PM concentration. However, even thi...

HPO2Vec+: Leveraging heterogeneous knowledge resources to enrich node embeddings for the Human Phenotype Ontology.

Journal of biomedical informatics
BACKGROUND: In precision medicine, deep phenotyping is defined as the precise and comprehensive analysis of phenotypic abnormalities, aiming to acquire a better understanding of the natural history of a disease and its genotype-phenotype associations...

Trader as a new optimization algorithm predicts drug-target interactions efficiently.

Scientific reports
Several machine learning approaches have been proposed for predicting new benefits of the existing drugs. Although these methods have introduced new usage(s) of some medications, efficient methods can lead to more accurate predictions. To this end, w...

EternaBrain: Automated RNA design through move sets and strategies from an Internet-scale RNA videogame.

PLoS computational biology
Emerging RNA-based approaches to disease detection and gene therapy require RNA sequences that fold into specific base-pairing patterns, but computational algorithms generally remain inadequate for these secondary structure design tasks. The Eterna p...

Adaptive Reinforcement Learning Neural Network Control for Uncertain Nonlinear System With Input Saturation.

IEEE transactions on cybernetics
In this paper, an adaptive neural network (NN) control problem is investigated for discrete-time nonlinear systems with input saturation. Radial-basis-function (RBF) NNs, including critic NNs and action NNs, are employed to approximate the utility fu...