AIMC Topic: Algorithms

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Machine learning analysis of DNA methylation profiles distinguishes primary lung squamous cell carcinomas from head and neck metastases.

Science translational medicine
Head and neck squamous cell carcinoma (HNSC) patients are at risk of suffering from both pulmonary metastases or a second squamous cell carcinoma of the lung (LUSC). Differentiating pulmonary metastases from primary lung cancers is of high clinical i...

Magnetic Resonance Fingerprinting Reconstruction Using Recurrent Neural Networks.

Studies in health technology and informatics
Magnetic Resonance Fingerprinting (MRF) is an imaging technique acquiring unique time signals for different tissues. Although the acquisition is highly accelerated, the reconstruction time remains a problem, as the state-of-the-art template matching ...

Analysis of machine learning algorithms as integrative tools for validation of next generation sequencing data.

European review for medical and pharmacological sciences
OBJECTIVE: While next generation sequencing (NGS) has become the technology of choice for clinical diagnostics, most genetic laboratories still use Sanger sequencing for orthogonal confirmation of NGS results. Previous studies have shown that when th...

Sound source ranging using a feed-forward neural network trained with fitting-based early stopping.

The Journal of the Acoustical Society of America
When a feed-forward neural network (FNN) is trained for acoustic source ranging in an ocean waveguide, it is difficult evaluating the FNN ranging accuracy of unlabeled test data. The label is the distance between source and receiver array. A fitting-...

Clinical Data Extraction and Normalization of Cyrillic Electronic Health Records Via Deep-Learning Natural Language Processing.

JCO clinical cancer informatics
PURPOSE: A substantial portion of medical data is unstructured. Extracting data from unstructured text presents a barrier to advancing clinical research and improving patient care. In addition, ongoing studies have been focused predominately on the E...

Machine-Learning and Stochastic Tumor Growth Models for Predicting Outcomes in Patients With Advanced Non-Small-Cell Lung Cancer.

JCO clinical cancer informatics
PURPOSE: The prediction of clinical outcomes for patients with cancer is central to precision medicine and the design of clinical trials. We developed and validated machine-learning models for three important clinical end points in patients with adva...

Prediction of Drug Approval After Phase I Clinical Trials in Oncology: RESOLVED2.

JCO clinical cancer informatics
PURPOSE: Drug development in oncology currently is facing a conjunction of an increasing number of antineoplastic agents (ANAs) candidate for phase I clinical trials (P1CTs) and an important attrition rate for final approval. We aimed to develop a ma...