AIMC Topic: Algorithms

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MALDI-TOF mass spectrometry combined with machine learning algorithms to identify protein profiles related to malaria infection in human sera from Côte d'Ivoire.

Malaria journal
BACKGROUND: In sub-Saharan Africa, Plasmodium falciparum is the most prevalent species of malaria parasites. In endemic areas, malaria is mainly diagnosed using microscopy or rapid diagnostic tests (RDTs), which have limited sensitivity, and microsco...

GRLGRN: graph representation-based learning to infer gene regulatory networks from single-cell RNA-seq data.

BMC bioinformatics
BACKGROUND: A gene regulatory network (GRN) is a graph-level representation that describes the regulatory relationships between transcription factors and target genes in cells. The reconstruction of GRNs can help investigate cellular dynamics, drug d...

AI analysis for ejection fraction estimation from 12-lead ECG.

Scientific reports
Heart failure (HF) remains a leading global cause of cardiovascular deaths, with its prevalence expected to rise in the upcoming decade. Measuring the heart ejection fraction (EF) is crucial for diagnosing and monitoring HF. Although echocardiography...

DrugGen enhances drug discovery with large language models and reinforcement learning.

Scientific reports
Traditional drug design faces significant challenges due to inherent chemical and biological complexities, often resulting in high failure rates in clinical trials. Deep learning advancements, particularly generative models, offer potential solutions...

Comparative analysis of heart disease prediction using logistic regression, SVM, KNN, and random forest with cross-validation for improved accuracy.

Scientific reports
This primary research paper emphasizes cross-validation, where data samples are reshuffled in each iteration to form randomized subsets divided into n folds. This method improves model performance and achieves higher accuracy than the baseline model....

Daily Automated Prediction of Delirium Risk in Hospitalized Patients: Model Development and Validation.

JMIR medical informatics
BACKGROUND: Delirium is common in hospitalized patients and is correlated with increased morbidity and mortality. Despite this, delirium is underdiagnosed, and many institutions do not have sufficient resources to consistently apply effective screeni...

Tailored self-supervised pretraining improves brain MRI diagnostic models.

Computerized medical imaging and graphics : the official journal of the Computerized Medical Imaging Society
Self-supervised learning has shown potential in enhancing deep learning methods, yet its application in brain magnetic resonance imaging (MRI) analysis remains underexplored. This study seeks to leverage large-scale, unlabeled public brain MRI datase...

Circular RNA discovery with emerging sequencing and deep learning technologies.

Nature genetics
Circular RNA (circRNA) represents a type of RNA molecule characterized by a closed-loop structure that is distinct from linear RNA counterparts. Recent studies have revealed the emerging role of these circular transcripts in gene regulation and disea...

BL-FlowSOM: Consistent and Highly Accelerated FlowSOM Based on Parallelized Batch Learning.

Cytometry. Part A : the journal of the International Society for Analytical Cytology
The recent increase in the dimensionality of cytometry data has led to the development of various computational analysis methods. FlowSOM is one of the best-performing clustering methods but has room for improvement in terms of the consistency and sp...

An Approach for Detecting Mangrove Areas and Mapping Species Using Multispectral Drone Imagery and Deep Learning.

Sensors (Basel, Switzerland)
Mangrove ecosystems are important in tropical and subtropical coastal zones, contributing to marine biodiversity and maintaining marine ecological balance. It is crucial to develop more efficient, intelligent, and accurate monitoring methods for mang...