AIMC Topic: Animals
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Machine Learning-Enhanced Single-Particle Tracking for Rapid Screening of Tumor Immunomodulatory Drugs.
ACS nano
Jul 21, 2025
The tumor microenvironment plays a critical role in tumor progression and immune response, with the extracellular matrix (ECM) regulating immune cell infiltration. However, the interplay between ECM dynamics and tumor immunity remains poorly understo...
Efficient Compression of Mass Spectrometry Images via Contrastive Learning-Based Encoding.
Analytical chemistry
Jul 21, 2025
In this study, we introduce a novel encoding algorithm utilizing contrastive learning to address the substantial data size challenges inherent in mass spectrometry imaging. Our algorithm compresses MSI data into fixed-length vectors, significantly re...
"Small extracellular vesicles: messengers at the service of breast cancer agenda in the primary and distant microenvironments".
Journal of experimental & clinical cancer research : CR
Jul 21, 2025
Breast cancer (BC) remains a leading cause of cancer-related mortality in women, with complex mechanisms driving its initiation, progression, and resistance to therapy. In recent years, the tumor microenvironment (TME) has gained attention for its cr...
Manipulation of neuronal activity by an artificial spiking neural network implemented on a closed-loop brain-computer interface in non-human primates.
Journal of neural engineering
Jul 21, 2025
Closed-loop brain-computer interfaces can be used to bridge, modulate, or repair damaged connections within the brain to restore functional deficits. Towards this goal, we demonstrate that small artificial spiking neural networks can be bidirectional...
Hybrid deep learning optimization for smart agriculture: Dipper throated optimization and polar rose search applied to water quality prediction.
PloS one
Jul 21, 2025
Modern sustainable farming demands precise water management techniques, particularly for crops like potatoes that require high-quality irrigation to ensure optimal growth. This study presents a novel hybrid metaheuristic framework that combines Dippe...
Quantitative modeling of mortality patterns in dogs exposed to alpha particle emitting radionuclides: Insights from competing risks and causal inference machine learning.
PloS one
Jul 21, 2025
This study employed state-of-the-art machine learning to evaluate the mortality effects of alpha-emitting radionuclides (241Am, 249Cf, 252Cf, 238Pu, 239Pu, 224Ra, 226Ra, 228Th) on 2,576 dogs, factoring in radioactivity levels, composition, administra...
Exploration of common pathogenic genes between cerebral amyloid angiopathy and insomnia based on bioinformatics and experimental validation.
Scientific reports
Jul 20, 2025
Cerebral amyloid angiopathy (CAA) and insomnia are age-related neurological disorders increasingly recognized as being closely associated. However, research on the shared genes and their biological mechanisms remains limited. This study aims to ident...
Computer vision to predict cell seeding coverage in re-endothelialized mouse lungs.
Scientific reports
Jul 19, 2025
Transplantation of donor grafts recellularized with recipient-derived or non-immunogenic universal cells is a potential means of reducing the graft rejection and post-transplant complications in lung transplantation. Achieving a fully recellularized ...
Artificial intelligence-driven computational methods for antibody design and optimization.
mAbs
Jul 18, 2025
Antibodies play a crucial role in our immune system. Their ability to bind to and neutralize pathogens opens opportunities to develop antibodies for therapeutic and diagnostic use. Computational methods capable of designing antibodies for a target an...
Deep Learning-Based Multimodal Fusion Approach for Predicting Acute Dermal Toxicity.
Journal of chemical information and modeling
Jul 18, 2025
Acute dermal toxicity testing is essential for assessing the safety of chemicals used in pharmaceuticals, pesticides, cosmetics, and industrial chemicals. Conventional toxicity testing methods rely significantly on animal tests, which are resource-in...
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