AIMC Topic: Animals

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[Research progress of effect mechanism of acupotomy for knee osteoarthritis].

Zhongguo zhen jiu = Chinese acupuncture & moxibustion Mar 31, 2025
Acupotomy therapy demonstrates the definite clinical efficacy on knee osteoarthritis (KOA). After reviewing systematically the mechanism studies on acupotomy for KOA over the past 5 years, It is revealed that acupotomy synergistically intervenes in t...
Humans Osteoarthritis, Knee Animals Acupuncture Therapy
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Scaling Up Synthetic Cell Production Using Robotics and Machine Learning Toward Therapeutic Applications.

Advanced biology Mar 31, 2025
Synthetic cells (SCs), developed through bottom-up synthetic biology, hold great potential for biomedical applications, with the promise of replacing malfunctioning natural cells and treating diseases with spatiotemporal control. Currently, most SC s...
Artificial Cells Robotics Synthetic Biology Animals Mice Machine Learning
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Causal machine learning for single-cell genomics.

Nature genetics Mar 31, 2025
Advances in single-cell '-omics' allow unprecedented insights into the transcriptional profiles of individual cells and, when combined with large-scale perturbation screens, enable measuring of the effect of targeted perturbations on the whole transc...
Machine Learning Humans Single-Cell Analysis Gene Expression Profiling Genomics Animals Transcriptome
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The reality of modeling irritable bowel syndrome: progress and challenges.

Expert opinion on drug discovery Mar 31, 2025
INTRODUCTION: Irritable bowel syndrome (IBS) is a common gastrointestinal disorder that is often therapeutically challenging. While research has advanced our understanding of IBS pathophysiology, developing precise models to predict drug response and...
Drug Development Disease Models, Animal Irritable Bowel Syndrome Gastrointestinal Agents Reproducibility of Results Animals Artificial Intelligence Computer Simulation Humans
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Integration of epigenomic and genomic data to predict residual feed intake and the feed conversion ratio in dairy sheep via machine learning algorithms.

BMC genomics Mar 31, 2025
BACKGROUND: Feed efficiency (FE) is an essential trait in livestock species because of the constant demand to increase the productivity and sustainability of livestock production systems. A better understanding of the biological mechanisms associated...
Genomics Sheep Epigenomics Eating Machine Learning Female DNA Methylation Algorithms Animal Feed Animals
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Ultrastructural Morphometry of Mitochondria: Comparison Between Conventional Operator-Dependent and Artificial Intelligence (AI)-Operated Machine Learning Methods.

Microscopy research and technique Mar 29, 2025
Morphometric analysis of digital images is fundamental to substantiate the visual observations with objective quantitative data suitable for statistical analysis. The recent advances in artificial intelligence (AI) have allowed the development of mac...
Humans Artificial Intelligence Image Processing, Computer-Assisted Mitochondria Microscopy, Electron, Transmission Machine Learning Animals
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Deep structural brain imaging via computational three-photon microscopy.

Journal of biomedical optics Mar 29, 2025
SIGNIFICANCE: High-resolution optical imaging at significant depths is challenging due to scattering, which impairs image quality in living matter with complex structures. We address the need for improved imaging techniques in deep tissues.
Mice Brain Hippocampus Signal-To-Noise Ratio Microscopy, Fluorescence, Multiphoton Neuroimaging Imaging, Three-Dimensional Animals Image Processing, Computer-Assisted Deep Learning
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Use of robotics in broiler production systems: a relationship between technology, environment and production.

Tropical animal health and production Mar 29, 2025
In poultry farming, robotics is represented by robotic models which perform different functions. Among these functions, ambience is one of the most critical, as the aviary is an artificial environment which needs to present all the necessary conditio...
Housing, Animal Environment Animals Animal Husbandry Chickens Robotics
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Estimation of irradiation doses in chicken samples using a reaction-based fingerprinting method.

Food chemistry Mar 28, 2025
Food irradiation on an industrial scale calls for the development of rapid and inexpensive methods for the dose estimation after irradiation. An emerging solution to this problem is a reaction-based optical sensing strategy that is based on monitorin...
Animals Chickens Meat Food Irradiation
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Deep learning in the discovery of antiviral peptides and peptidomimetics: databases and prediction tools.

Molecular diversity Mar 28, 2025
Antiviral peptides (AVPs) represent a novel and promising therapeutic alternative to conventional antiviral treatments, due to their broad-spectrum activity, high specificity, and low toxicity. The emergence of zoonotic viruses such as Zika, Ebola, a...
Peptidomimetics Deep Learning Antiviral Agents Databases, Factual SARS-CoV-2 Humans Animals COVID-19 Peptides Drug Discovery
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