International journal of pharmaceutics
Jul 24, 2025
This critical review provided a detailed strengths, weaknesses, opportunities, and threats (SWOT) analysis of nebulized liposomal formulations, focusing on the strengths and translational potential. The formulations have notable strengths, such as en...
Filoviruses such as Ebola virus (EBOV) give rise to frequent epidemics with high case fatality rates while therapeutic options remain limited. Earlier genetic screens aimed to identify potential drug targets for EBOV relied on systems that may not fu...
BACKGROUND: Pancreatic cellular heterogeneity is fundamental to systemic metabolic regulation, yet its pathological remodeling in diabetes remains poorly characterized.
In nature, the dynamic contraction and relaxation of muscle in animals provide the essential force and deformation necessary for diverse locomotion, enabling them to navigate and overcome environmental challenges. However, most autonomous robotic sys...
There is a widespread perception that illegal fishing is common in marine protected areas (MPAs) due to strong incentives for poaching and the high cost of monitoring and enforcement. Using artificial intelligence and satellite-based Earth observatio...
Cancer remains one of the leading causes of death worldwide, with therapy resistance and tumor recurrence driven by a subpopulation of cells known as cancer stem cells (CSCs). CSCs possess a remarkable ability to evade apoptosis, adapt to harsh micro...
Porcine epidemic diarrhea is a highly contagious intestinal disease in pigs, caused by various strains of porcine epidemic diarrhea virus (PEDV). The infection rate in suckling piglets can reach 100%. Manual analysis of pathological images is the pri...
Novel insights into cardiac contractile dysfunction at the cellular level could deepen understanding of arrhythmia and heart injury, which are leading causes of morbidity and mortality worldwide. We present a comprehensive experimental and computatio...
Accurate estimation of the postmortem interval (PMI) is crucial for medico-legal investigations, providing critical timelines for criminal cases. Current PMI methods, however, often lack precision, limiting their forensic utility. In this study, we d...
Trained immunity presents a unique target for modulating the immune response against infectious and non-infectious threats to human health. To address the unmet need for training-targeted therapies, we explore bioengineering methods to answer researc...
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