AIMC Topic: Animals

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Prediction and Prioritisation of Novel Anthelmintic Candidates from Public Databases Using Deep Learning and Available Bioactivity Data Sets.

International journal of molecular sciences Mar 28, 2025
The control of socioeconomically important parasitic roundworms (nematodes) of animals has become challenging or ineffective due to problems associated with widespread resistance in these worms to most classes of chemotherapeutic drugs (anthelmintics...
Deep Learning Haemonchus Anthelmintics Computer Simulation Animals Drug Discovery Databases, Factual
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Stable heteroclinic channels as a decision-making model: overcoming low signal-to-noise ratio with mutual inhibition.

Bioinspiration & biomimetics Mar 28, 2025
Bio-inspired robot controllers are becoming more complex as we strive to make them more robust to, and flexible in, noisy, real-world environments. A stable heteroclinic network (SHN) is a dynamical system that produces cyclical state transitions usi...
Computer Simulation Biomimetics Signal-To-Noise Ratio Animals Robotics
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Comparative Assessment of Manual Segmentation of Cerebral Infarction Lesions in Experimental Animals Based on Magnetic Resonance Imaging Using Artificial Intelligence.

Bulletin of experimental biology and medicine Mar 28, 2025
The aim of this study was to evaluate the quality of manual segmentation of cerebral infarction lesions in experimental animals with modeled brain infarct based on magnetic resonance imaging compared to an automated artificial intelligence approach. ...
Male Image Processing, Computer-Assisted Magnetic Resonance Imaging Disease Models, Animal Rats Reproducibility of Results Animals Artificial Intelligence Cerebral Infarction Brain
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Unveiling the power of Treg.Sig: a novel machine-learning derived signature for predicting ICI response in melanoma.

Frontiers in immunology Mar 28, 2025
BACKGROUND: Although immune checkpoint inhibitor (ICI) represents a significant breakthrough in cancer immunotherapy, only a few patients benefit from it. Given the critical role of Treg cells in ICI treatment resistance, we explored a Treg-associate...
STAT1 Transcription Factor T-Lymphocytes, Regulatory Drug Resistance, Neoplasm Gene Expression Profiling Mice Immune Checkpoint Inhibitors Humans Transcriptome Melanoma Gene Expression Regulation, Neoplastic Animals Machine Learning
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A hybrid long short-term memory-convolutional neural network multi-stream deep learning model with Convolutional Block Attention Module incorporated for monkeypox detection.

Science progress Mar 28, 2025
BackgroundMonkeypox (mpox) is a zoonotic infectious disease caused by the mpox virus and characterized by painful body lesions, fever, headaches, and exhaustion. Since the report of the first human case of mpox in Africa, there have been multiple out...
Humans Neural Networks, Computer Memory, Short-Term Mpox, Monkeypox Monkeypox virus Animals Deep Learning
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Soft robotic brittle star shows the influence of mass distribution on underwater walking.

Bioinspiration & biomimetics Mar 27, 2025
Most walking organisms tend to have relatively light limbs and heavy bodies in order to facilitate rapid limb motion. However, the limbs of brittle stars (Class Ophiuroidea) are primarily comprised of dense skeletal elements, with potentially much hi...
Computer Simulation Models, Biological Biomimetics Echinodermata Locomotion Equipment Design Walking Animals Robotics
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Bridging the gap between histopathology and genomics: Spotlighting spatial omics.

Veterinary pathology Mar 26, 2025
Spatial biology has emerged as a transformative field, offering insights into cellular interactions and organization within tissues. The field has evolved rapidly since the coining of the term "spatial omics." Now, the ability to spatially resolve pr...
Animals Genomics Pathology, Veterinary
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Advancements in small molecule fluorescent probes for the detection of formaldehyde in environmental and food samples: A comprehensive review.

Food chemistry Mar 26, 2025
Formaldehyde (FA), a hazardous substance with carcinogenicity and mutagenicity, necessitates sensitive and accurate detection methods for protecting public health and the environment. While numerous reviews have explored FA fluorescent probes, the cu...
Food Contamination Humans Food Analysis Fluorescent Dyes Animals Formaldehyde Environmental Pollutants Environmental Monitoring
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Bat-Inspired Bionic Bimodal Active Cognitive Electronic Skin with Multisensory Integration Ability.

Nano letters Mar 26, 2025
Empowering intelligent robots with cognitive abilities that rival or even surpass those of humans is the key to enabling more complex and sophisticated interactions. Currently, most electronic skins (e-skins) perform excellently in distinguishing sha...
Chiroptera Bionics Cognition Robotics Animals Wearable Electronic Devices Humans Machine Learning
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Soft Biological Actuators for Meter-Scale Homeostatic Biohybrid Robots.

Chemical reviews Mar 26, 2025
Skeletal muscle's elegant protein-based architecture powers motion throughout the animal kingdom, with its constituent actomyosin complexes driving intra- and extra-cellular motion. Classical motors and recently developed soft actuators cannot match ...
Tissue Engineering Homeostasis Robotics Biocompatible Materials Animals Muscle, Skeletal Humans
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