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T-Lymphocytes, Regulatory

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[Effect of moxa-cone moxibustion at lung's back- points and front- points on Th17/Treg balance in mice with asthma].

Zhongguo zhen jiu = Chinese acupuncture & moxibustion
OBJECTIVE: To observe the effect of moxa-cone moxibustion at lung's back- points and front- points on the expression of helper T lymphocyte 17 (Th 17)/regulatory T lymphocyte (Treg) in mice with asthma, and to explore the possible mechanism of moxa-c...

Role of α-fetoprotein in differentiation of regulatory T lymphocytes.

Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections
The effect of native α-fetoprotein (AFP) on the expression of T-regulatory lymphocyte (Treg) markers by activated CD4 lymphocytes with different proliferative status was studied. α-Fetoprotein did not affect the ratio of proliferating and non-prolife...

[Prophylactic administration of all-trans retinoic acid alleviates inflammation in rats with collagen-induced arthritis].

Nan fang yi ke da xue xue bao = Journal of Southern Medical University
OBJECTIVE: To investigate the effects of prophylactic administration of all-trans retinoic acid (ATRA) in relieving inflammation in a rat model of collagen-induced arthritis (CIA).

Immune-Based Prediction of COVID-19 Severity and Chronicity Decoded Using Machine Learning.

Frontiers in immunology
Expression of CCR5 and its cognate ligands have been implicated in COVID-19 pathogenesis, consequently therapeutics directed against CCR5 are being investigated. Here, we explored the role of CCR5 and its ligands across the immunologic spectrum of CO...

Blood-Based Immune Profiling Combined with Machine Learning Discriminates Psoriatic Arthritis from Psoriasis Patients.

International journal of molecular sciences
Psoriasis (Pso) is a chronic inflammatory skin disease, and up to 30% of Pso patients develop psoriatic arthritis (PsA), which can lead to irreversible joint damage. Early detection of PsA in Pso patients is crucial for timely treatment but difficult...

Unveiling the power of Treg.Sig: a novel machine-learning derived signature for predicting ICI response in melanoma.

Frontiers in immunology
BACKGROUND: Although immune checkpoint inhibitor (ICI) represents a significant breakthrough in cancer immunotherapy, only a few patients benefit from it. Given the critical role of Treg cells in ICI treatment resistance, we explored a Treg-associate...