Journal of biochemical and molecular toxicology
Jun 1, 2025
Experimental model systems, especially animal models, are indispensable tools to study human diseases and to develop new therapeutics. Chronic kidney disease (CKD) is a major global health problem having significantly higher rate of morbidity and mor...
Photodiagnosis and photodynamic therapy
Jun 1, 2025
Photobiomodulation therapy (PBMT) emerged as a significant non-invasive method of stimulating regeneration of the skeletal muscle tissue. This review considers the pathophysiologic and molecular mechanisms of muscle repair, with a focus on the impera...
Deep learning label-free cell imaging has become essential in modern medical applications, enabling precise cell analysis while preserving natural biological functions and structures by removing the need for potentially disruptive staining reagents. ...
Regulatory agencies require comprehensive toxicity testing for prenatal drug exposure, including new drugs in development, to reduce concerns about developmental toxicity, that is, drug-induced toxicity and adverse effects in pregnant women and fetus...
Coral reef systems are facing unprecedented pressures due to climate change, and stable coral rubble substrates are crucial for facilitating large-scale coral regeneration. This study integrates the Sixth Phase of the Coupled Model Intercomparison Pr...
Protein science : a publication of the Protein Society
Jun 1, 2025
Protein aggregation is associated with a spectrum of neurodegenerative diseases. Although many small ligands have been found to modulate or inhibit protein aggregation, their molecular mechanisms remain unclear. One reason for this is the inherent he...
Perfluorooctanoic acid (PFOA), a widely used industrial chemical, poses significant environmental and biological toxicity, particularly affecting reproductive health. This study aimed to integrate network toxicology, machine learning, and molecular d...
The international journal of medical robotics + computer assisted surgery : MRCAS
Jun 1, 2025
BACKGROUND: In endoscopic surgery, surgeons collaborate with assistants to manipulate the endoscope and instruments, making it impossible to perform the surgery independently.
Pflugers Archiv : European journal of physiology
Jun 1, 2025
The renal thick ascending limb (TAL) plays a key role in water and ion homeostasis. Apical potassium secretion via the renal outer medullary potassium channel (ROMK) is essential for transepithelial sodium reabsorption via the furosemide-sensitive Na...
This study aims to investigate the effects of upper skin layers on laser light propagation and heat diffusion during laser surgery for vascular dermatosis. Using a rat dorsal window chamber model, deep-situated vessels are irradiated by a transcutane...
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