Cells are regulated at multiple levels, from regulations of individual genes to interactions across multiple genes. Some recent neural network models can connect molecular changes to cellular phenotypes, but their design lacks modeling of regulatory ...
In the wagyu industry worldwide, high-quality marbling beef is produced by promoting intramuscular fat deposition during cattle fattening stage through dietary vitamin A control. Thus, however, cattle become susceptible to either vitamin A deficiency...
The selection of high-performing cell lines is crucial for biopharmaceutical production but is often time-consuming and labor-intensive. We investigated label-free multimodal nonlinear optical microscopy for non-perturbative profiling of biopharmaceu...
With bio-medical wearables becoming an essential part of Internet of Medical things (IoMT) for monitoring the health of workers, patients and others in different environments, antenna play a pivotal role in such wearables. In this communication, a no...
Expert opinion on drug metabolism & toxicology
Feb 2, 2025
INTRODUCTION: Drug-induced liver injury (DILI) is a leading cause of acute liver failure. Hepatotoxicity typically occurs only in a subset of individuals after prolonged exposure and constitutes a major risk factor for the termination of drug develop...
Current artificial systems suffer from catastrophic forgetting during continual learning, a limitation absent in biological systems. Biological mechanisms leverage the dual representation of specific and generalized memories within corticohippocampal...
Stingless bee honey is emerging as a superfood, given its enhanced health and therapeutic benefits. In this paper, we used handheld X-ray fluorescence spectroscopy (hXRF) with machine learning techniques to classify Philippine honey based on its ento...
The surface modification of titanium (Ti) and its alloys is crucial for improving their osteogenic capability, as their bio-inert nature limits effective osseointegration despite their prevalent use in orthopedic implants. However, these modification...
The brain's ability to learn and distinguish rapid sequences of events is essential for timing-dependent tasks, such as those in sports and music. However, the mechanisms underlying this ability remain an active area of research. Here, we present a P...
Food research international (Ottawa, Ont.)
Feb 1, 2025
Current detection methods for lipid and protein oxidation using hyperspectral imaging (HSI) in conjunction with machine learning (ML) necessitate the involvement of data scientists and domain experts to adjust the model architecture and tune hyperpar...
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