AIMC Topic: Anti-Infective Agents

Clear Filters Showing 21 to 30 of 92 articles

Antimicrobial Activity of Extract Used for Potential Application in the Prevention and Treatment of Oral Diseases.

Medicina (Kaunas, Lithuania) Dec 21, 2023
: This study evaluated the antimicrobial effect and cytotoxic potential of the natural extract against (), the causative agent of dental caries, which is a typical oral disease, and (), which causes oral candidiasis. : was shaken in 70% ethanol f...
Humans Anti-Infective Agents Streptococcus mutans Candida albicans Dental Caries Biofilms Plant Extracts
View on PubMed DOI

Editorial: Clinical impact of fast platforms and laboratory automation for the rapid diagnosis of infectious diseases and detection of antimicrobial resistance determinants.

Frontiers in cellular and infection microbiology Dec 4, 2023
Communicable Diseases Anti-Bacterial Agents Humans Anti-Infective Agents Drug Resistance, Bacterial Automation, Laboratory
View on PubMed DOI

E. globulus leaf EO exhibits anti-inflammatory effects by regulating GSDMD-mediated pyroptosis, thereby alleviating neurological impairment and neuroinflammation in experimental stroke mice.

Journal of ethnopharmacology Oct 30, 2023
ETHNOPHARMACOLOGICAL RELEVANCE: Aromatic and medicinal plants continue to be a major component of alternative and traditional medicine in the developing countries. Eucalyptus globulus (Labill.) is being employed to cultivation and production in China...
Rats Stroke Inflammation Infarction, Middle Cerebral Artery Animals DNA-Binding Proteins Mice NLR Family, Pyrin Domain-Containing 3 Protein NF-kappa B Plant Leaves Pyroptosis Tumor Necrosis Factor-alpha Anti-Inflammatory Agents Anti-Infective Agents Rats, Sprague-Dawley Neuroinflammatory Diseases Interleukin-6 Lipopolysaccharides Microglia
View on PubMed DOI

Antimicrobial treatment imprecision: an outcome-based model to close the data-to-action loop.

The Lancet. Infectious diseases Aug 31, 2023
Health-care systems, food supply chains, and society in general are threatened by the inexorable rise of antimicrobial resistance. This threat is driven by many factors, one of which is inappropriate antimicrobial treatment. The ability of policy mak...
Humans Policy Public Health Health Facilities Artificial Intelligence Anti-Infective Agents
View on PubMed DOI

Leveraging artificial intelligence in the fight against infectious diseases.

Science (New York, N.Y.) Jul 13, 2023
Despite advances in molecular biology, genetics, computation, and medicinal chemistry, infectious disease remains an ominous threat to public health. Addressing the challenges posed by pathogen outbreaks, pandemics, and antimicrobial resistance will ...
Communicable Disease Control Drug Discovery Humans Communicable Diseases Public Health Artificial Intelligence Pandemics Anti-Infective Agents
View on PubMed DOI

Artificial intelligence as a smart approach to develop antimicrobial drug molecules: A paradigm to combat drug-resistant infections.

Drug discovery today Jan 13, 2023
Antimicrobial resistance (AMR) is a silent pandemic with the third highest global mortality. The antibiotic development pipeline is scarce even though AMR has escalated uncontrollably. Artificial intelligence (AI) is a revolutionary approach, acceler...
Anti-Infective Agents Drug Discovery Artificial Intelligence Anti-Bacterial Agents
View on PubMed DOI

Text mining for identification of biological entities related to antibiotic resistant organisms.

PeerJ May 5, 2022
Antimicrobial resistance is a significant public health problem worldwide. In recent years, the scientific community has been intensifying efforts to combat this problem; many experiments have been developed, and many articles are published in this a...
Algorithms Anti-Infective Agents Data Mining Artificial Intelligence Machine Learning
View on PubMed DOI

Machine learning to design antimicrobial combination therapies: Promises and pitfalls.

Drug discovery today Apr 7, 2022
Combination therapies can overcome antimicrobial resistance (AMR) and repurpose existing drugs. However, the large combinatorial space to explore presents a daunting challenge. In response, machine learning (ML) algorithms are being applied to identi...
Algorithms Anti-Bacterial Agents Anti-Infective Agents Machine Learning
View on PubMed DOI

Overcoming challenges in extracting prescribing habits from veterinary clinics using big data and deep learning.

Australian veterinary journal Jan 25, 2022
Understanding antimicrobial usage patterns and encouraging appropriate antimicrobial usage is a critical component of antimicrobial stewardship. Studies using VetCompass Australia and Natural Language Processing (NLP) have demonstrated antimicrobial ...
Big Data Habits Animals Deep Learning Hospitals, Animal Anti-Bacterial Agents Anti-Infective Agents
View on PubMed DOI

Assessing and utilizing esterase specificity in antimicrobial prodrug development.

Methods in enzymology Dec 23, 2021
As a class of enzymes, esterases have been investigated for decades and have found use in industrial processes, synthetic organic chemistry, and elsewhere. Esters are functional groups composed of an alcohol moiety and a carboxylic acid moiety. Altho...
Esters Prodrugs Anti-Bacterial Agents Hydrolysis Esterases Anti-Infective Agents
View on PubMed DOI
Popular Topics
Recent Journals