AIMC Topic: Area Under Curve

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Comprehensive Drug-Likeness Prediction Using a Pretrained Transformer Model and Multitask Learning.

Journal of chemical information and modeling
Drug-likeness is essential in drug discovery, indicating the potential of a compound to become a successful therapeutic. However, existing rule-based and machine learning methods are limited by their reliance on hand-crafted features, poor generaliza...

Four Different Artificial Intelligence Models Logistic Regression to Enhance the Diagnostic Accuracy of Fecal Immunochemical Test in the Detection of Colorectal Carcinoma in a Screening Setting.

Anticancer research
BACKGROUND/AIM: This study aimed to evaluate the diagnostic accuracy (DA) of four artificial intelligence (AI) models compared to logistic regression (LR) in enhancing the performance of the fecal immunochemical test (FIT) for the detection of colore...

Effect of Cumulative Exposure on the Efficacy of Paroxetine: A Population Pharmacokinetic-Pharmacodynamic and Machine Learning Analyses.

CPT: pharmacometrics & systems pharmacology
Selective serotonin reuptake inhibitors (SSRIs) are widely used in depression treatment. However, the relationship between treatment efficacy and plasma concentrations remains unclear. We assessed whether the anti-depressive response can be predicted...

Towards robust multimodal ultrasound classification for liver tumor diagnosis: A generative approach to modality missingness.

Computer methods and programs in biomedicine
BACKGROUND AND OBJECTIVE: In medical image analysis, combining multiple imaging modalities enhances diagnostic accuracy by providing complementary information. However, missing modalities are common in clinical settings, limiting the effectiveness of...

Comparison of machine learning models for predicting stroke risk in hypertensive patients: Lasso regression model, random forest model, Boruta algorithm model, and Boruta algorithm combined with Lasso regression model.

Medicine
The aim of this study was to compare the performance of 4 machine learning models-Lasso regression model, random forest model, Boruta algorithm model, and the Boruta algorithm combined with Lasso regression-in predicting stroke risk among hypertensiv...

Integrating SEResNet101 and SE-VGG19 for advanced cervical lesion detection: a step forward in precision oncology.

BMC cancer
BACKGROUND: Cervical cancer remains a significant global health issue, with accurate differentiation between low-grade (LSIL) and high-grade squamous intraepithelial lesions (HSIL) crucial for effective screening and management. Current methods, such...

Saliva-derived transcriptomic signature for gastric cancer detection using machine learning and leveraging publicly available datasets.

Scientific reports
Saliva, a non-invasive, self-collected liquid biopsy, holds promise for early gastric cancer (GC) screening. This study aims to assess the potential of saliva as a proxy for malignant gastric transformation and its diagnostic value through transcript...

Light Bladder Net: Non-invasive Bladder Cancer Prediction by Weighted Deep Learning Approaches and Graphical Data Transformation.

Anticancer research
BACKGROUND/AIM: Bladder cancer (BCa) is associated with high recurrence rates, emphasizing the importance of early and accurate detection. This study aimed to develop a lightweight and fast deep learning model, Light-Bladder-Net (LBN), for non-invasi...

An APRI+ALBI-Based Multivariable Model as a Preoperative Predictor for Posthepatectomy Liver Failure.

Annals of surgery
OBJECTIVE AND BACKGROUND: Clinically significant posthepatectomy liver failure (PHLF B+C) remains the main cause of mortality after major hepatic resection. This study aimed to establish an aspartate aminotransferase to platelet ratio combined with a...

Comparative Evaluation of Pre-Test Probability Models for Coronary Artery Disease with Assessment of a New Machine Learning-Based Model.

Yonsei medical journal
PURPOSE: This study aimed to validate pivotal pre-test probability (PTP)-coronary artery disease (CAD) models (CAD consortium model and IJC-CAD model).