AIMC Topic: Bacteria

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PaPrBaG: A machine learning approach for the detection of novel pathogens from NGS data.

Scientific reports
The reliable detection of novel bacterial pathogens from next-generation sequencing data is a key challenge for microbial diagnostics. Current computational tools usually rely on sequence similarity and often fail to detect novel species when closely...

Syntheses and antibacterial activity of soluble 9-bromo substituted indolizinoquinoline-5,12-dione derivatives.

European journal of medicinal chemistry
In our previous research, 9-bromo indolizinoquinoline-5,12-dione 1 has been found to be a good anti-MRSA agent. However, it had very low bioavailability in vivo possibly due to its low solubility in water. In order to obtain the derivatives with high...

Genomic Islands: an overview of current software and future improvements.

Journal of integrative bioinformatics
Microbes are highly diverse and widely distributed organisms. They account for ~60% of Earth’s biomass and new predictions point for the existence of 1011 to 1012 species, which are constantly sharing genes through several different mechanisms....

Spectral consensus strategy for accurate reconstruction of large biological networks.

BMC bioinformatics
BACKGROUND: The last decades witnessed an explosion of large-scale biological datasets whose analyses require the continuous development of innovative algorithms. Many of these high-dimensional datasets are related to large biological networks with f...

Regulatory efficacy of fermented plant extract on the intestinal microflora and lipid profile in mildly hypercholesterolemic individuals.

Journal of food and drug analysis
In recent years, the use of fermented plant products to protect against various metabolic syndromes has been increasing enormously. The objective of this study was to check the regulatory efficacy of fermented plant extract (FPE) on intestinal microf...

THE BIOLOGICAL ACTIVITIES OF L.

African journal of traditional, complementary, and alternative medicines : AJTCAM
BACKGROUND: Mastitis reduces milk yield and alters milk composition. Antibiotics are widely used in the treatment of the disease. However, this widespread use of antibiotics causes both antibiotic residues in milks and antibiotic resistance developed...

Assessment of bacterial quality of honey produced in Tamale metropolis (Ghana).

Journal of food and drug analysis
The bacterial quality of honey from different production sites within Tamale metropolis, Ghana, was estimated using standard microbiological methods. Honey samples were bought from six different production sites within Tamale metropolis and labeled. ...

Achieving partial nitrification by inhibiting the activity of Nitrospira-like bacteria under high-DO conditions in an intermittent aeration reactor.

Journal of environmental sciences (China)
It is generally accepted that a low dissolved oxygen (DO) concentration is more beneficial for achieving partial nitrification than high-DO. In this study, partial nitrification was not established under low-DO conditions in an intermittent aeration ...

Symbiont modulates expression of specific gene categories in Angomonas deanei.

Memorias do Instituto Oswaldo Cruz
Trypanosomatids are parasites that cause disease in humans, animals, and plants. Most are non-pathogenic and some harbor a symbiotic bacterium. Endosymbiosis is part of the evolutionary process of vital cell functions such as respiration and photosyn...

Prediction of bacterial associations with plants using a supervised machine-learning approach.

Environmental microbiology
Recent scenarios of fresh produce contamination by human enteric pathogens have resulted in severe food-borne outbreaks, and a new paradigm has emerged stating that some human-associated bacteria can use plants as secondary hosts. As a consequence, t...