AIMC Topic: Bacteria

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RABiTPy: an open-source Python software for rapid, AI-powered bacterial tracking and analysis.

BMC bioinformatics
Bacterial tracking is crucial for understanding the mechanisms governing motility, chemotaxis, cell division, biofilm formation, and pathogenesis. Although modern microscopy and computing have enabled the collection of large datasets, many existing t...

Deep learning enabled open-set bacteria recognition using surface-enhanced Raman spectroscopy.

Biosensors & bioelectronics
Accurate bacterial identification is vital in medical and healthcare settings. Traditional methods, though reliable, are often time-consuming, underscoring the need for faster, more efficient alternatives. Deep learning-assisted Surface-enhanced Rama...

Innovative fast and low-cost method for the detection of living bacteria based on trajectory.

Scientific reports
Detection of pathogens is a major concern in many fields like medicine, pharmaceuticals, or agri-food. Most conventional detection methods require skilled staff and specific laboratory equipment for sample collection and analysis or are specific to a...

Impact of Blastocystis carriage and colonization intensity on gut microbiota composition in a non-westernized rural population from Colombia.

PLoS neglected tropical diseases
BACKGROUND: The role of Blastocystis, a common intestinal parasitic protist of humans and other animals, in human health and disease remains elusive. Recent studies suggest a connection between Blastocystis colonization, healthier lifestyles, and hig...

Negative dataset selection impacts machine learning-based predictors for multiple bacterial species promoters.

Bioinformatics (Oxford, England)
MOTIVATION: Advances in bacterial promoter predictors based on machine learning have greatly improved identification metrics. However, existing models overlooked the impact of negative datasets, previously identified in GC-content discrepancies betwe...

PharaCon: a new framework for identifying bacteriophages via conditional representation learning.

Bioinformatics (Oxford, England)
MOTIVATION: Identifying bacteriophages (phages) within metagenomic sequences is essential for understanding microbial community dynamics. Transformer-based foundation models have been successfully employed to address various biological challenges. Ho...

MOSTPLAS: a self-correction multi-label learning model for plasmid host range prediction.

Bioinformatics (Oxford, England)
MOTIVATION: Plasmids play an essential role in horizontal gene transfer, aiding their host bacteria in acquiring beneficial traits like antibiotic and metal resistance. There exist some plasmids that can transfer, replicate, or persist in multiple or...

Using gut microbiome metagenomic hypervariable features for diabetes screening and typing through supervised machine learning.

Microbial genomics
Diabetes mellitus is a complex metabolic disorder and one of the fastest-growing global public health concerns. The gut microbiota is implicated in the pathophysiology of various diseases, including diabetes. This study utilized 16S rRNA metagenomic ...

Deep-Learning-Based Approaches for Rational Design of Stapled Peptides With High Antimicrobial Activity and Stability.

Microbial biotechnology
Antimicrobial peptides (AMPs) face stability and toxicity challenges in clinical use. Stapled modification enhances their stability and effectiveness, but its application in peptide design is rarely reported. This study built ten prediction models fo...

Predicting the bacterial host range of plasmid genomes using the language model-based one-class support vector machine algorithm.

Microbial genomics
The prediction of the plasmid host range is crucial for investigating the dissemination of plasmids and the transfer of resistance and virulence genes mediated by plasmids. Several machine learning-based tools have been developed to predict plasmid h...