Closed pelvic fractures can lead to severe complications, including hemodynamic instability (HI) and mortality. Accurate prediction of these risks is crucial for effective clinical management. This study aimed to utilize various machine learning (ML)...
European journal of drug metabolism and pharmacokinetics
May 8, 2025
BACKGROUND AND OBJECTIVE: Model-informed precision dosing (MIPD), based on a Bayesian approach and machine learning (ML) algorithms, is a suitable approach to personalize dosage recommendations and to improve the concentration target attainment for e...
Technology in cancer research & treatment
May 8, 2025
IntroductionMesothelioma is a type of lung cancer caused by asbestos exposure, and early diagnosis is crucial for improving survival chances. Artificial intelligence offers a potential solution for the timely diagnosis and staging of the disease. Thi...
The collapse accidents under cut and cover method in metro station construction occurred frequently, leading to severe casualties and property damage. With increasing of metro station construction in China, more and more attention has been paid to co...
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences
May 3, 2025
The concept of Design Space (DS), delineated as a region of investigated variables aimed at maintaining product quality, was introduced in the International Conference on Harmonisation (ICH) Q8 as a framework to direct pharmaceutical development. How...
IEEE transactions on neural networks and learning systems
May 2, 2025
Low-dose computed tomography (LDCT) image reconstruction techniques can reduce patient radiation exposure while maintaining acceptable imaging quality. Deep learning (DL) is widely used in this problem, but the performance of testing data (also known...
BACKGROUND: Large language models (LLMs) have flourished and gradually become an important research and application direction in the medical field. However, due to the high degree of specialization, complexity, and specificity of medicine, which resu...
Environmental monitoring and assessment
Apr 26, 2025
The suspended sediment load (SSL) of a river is a key indicator of water resource management, river morphology, and ecosystem health. This study analyzes historical changes in SSL and evaluates machine learning (ML) models for SSL prediction in the G...
Converting cellulose into 5-Hydroxymethylfurfural (HMF) provides a promising strategy for creating bio-based chemicals, offering sustainable alternatives to petroleum-based materials in polymers, biofuels, and pharmaceuticals. However, the efficient ...
Variants of Uncertain Significance (VUS) in genetic testing for hereditary diseases burden patients and clinicians, yet clinical data that could reduce VUS are underutilized due to a lack of scalable strategies. We assessed whether a machine learning...
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