The Morris Water Maze (MWM) is a widely used behavioral test to assess the spatial learning and memory of animals, particularly valuable in studying neurodegenerative disorders such as Alzheimer's disease. Traditional methods for analyzing MWM experi...
Surgical castration of males is carried out on a large scale in the US swine industry and the pain resulting from this procedure can be assessed using the Unesp-Botucatu pig composite acute pain scale (UPAPS). We aim to propose a short version of UPA...
Heat stress is a major welfare problem in the poultry industry, altering broilers' activity levels. Advancements in image processing and machine learning provide opportunities to automatically quantify and analyze broiler activity. This study aimed t...
Measuring and monitoring fish welfare in aquaculture research relies on the use of outcome- (biotic) and input-based (e.g., abiotic) welfare indicators (WIs). Incorporating behavioural auditing into this toolbox can sometimes be challenging because s...
Microplastics are widely distributed in the environment and pose potential hazards to organisms. However, our understanding of the transgenerational effects of microplastics on terrestrial organisms remains limited. In this study, we focused on the m...
The use of supervised machine learning to approximate poses in video recordings allows for rapid and efficient analysis of complex behavioral profiles. Currently, there are limited protocols for automated analysis of operant self-administration behav...
In experimental research, animal welfare should always be of the highest priority. Currently, physical in-person observations are the standard. This is time-consuming, and results are subjective. Video-based machine learning models for monitoring exp...
BACKGROUND: High-throughput behavioral analysis is important for drug discovery, toxicological studies, and the modeling of neurological disorders such as autism and epilepsy. Zebrafish embryos and larvae are ideal for such applications because they ...
Epilepsy, a neurological disorder causing recurring seizures, is often studied in zebrafish by exposing animals to pentylenetetrazol (PTZ), which induces clonic- and tonic-like behaviors. While adult zebrafish seizure-like behaviors are well characte...
Animal models and experimental medicine
Jan 23, 2025
BACKGROUND: Quantifying the rich home-cage activities of tree shrews provides a reliable basis for understanding their daily routines and building disease models. However, due to the lack of effective behavioral methods, most efforts on tree shrew be...
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