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Biomedical Research

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The Hearing Impairment Ontology: A Tool for Unifying Hearing Impairment Knowledge to Enhance Collaborative Research.

Genes
Hearing impairment (HI) is a common sensory disorder that is defined as the partial or complete inability to detect sound in one or both ears. This diverse pathology is associated with a myriad of phenotypic expressions and can be non-syndromic or sy...

Machine learning algorithm validation with a limited sample size.

PloS one
Advances in neuroimaging, genomic, motion tracking, eye-tracking and many other technology-based data collection methods have led to a torrent of high dimensional datasets, which commonly have a small number of samples because of the intrinsic high c...

A microsurgical robot research platform for robot-assisted microsurgery research and training.

International journal of computer assisted radiology and surgery
PURPOSE: Ocular surgery, ear, nose and throat surgery and neurosurgery are typical types of microsurgery. A versatile training platform can assist microsurgical skills development and accelerate the uptake of robot-assisted microsurgery (RAMS). Howev...

Predicting translational progress in biomedical research.

PLoS biology
Fundamental scientific advances can take decades to translate into improvements in human health. Shortening this interval would increase the rate at which scientific discoveries lead to successful treatment of human disease. One way to accomplish thi...

Trends and Focus of Machine Learning Applications for Health Research.

JAMA network open
IMPORTANCE: The use of machine learning applications related to health is rapidly increasing and may have the potential to profoundly affect the field of health care.

Automation With Intelligence in Drug Research.

Clinical therapeutics
The industry has adopted Clinical Data Interchange Standards Consortium standards for clinical trial data and the Food and Drug Administration electronic common technical document standard for documents for many years but still faces many challenges....

Neural network-based approaches for biomedical relation classification: A review.

Journal of biomedical informatics
The explosive growth of biomedical literature has created a rich source of knowledge, such as that on protein-protein interactions (PPIs) and drug-drug interactions (DDIs), locked in unstructured free text. Biomedical relation classification aims to ...