AIMC Topic: Biosensing Techniques

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Nonmagnetic Biomarker Detection by Nanocatalytic-Amplified Quantum Spin Relaxometry.

ACS nano
Nitrogen-vacancy (NV) centers in diamond demonstrate advantages in biosensing due to their exceptional photostability and long spin coherence time. However, clinical applications of NV centers are significantly limited because their spin states lack ...

Synthetic biology meets diagnostics: Engineering biosensing platforms for rapid and accurate pathogen and viral detection.

Biosensors & bioelectronics
The integration of synthetic biology with biosensor technologies has catalyzed a paradigm shift in the development of programmable, field-deployable diagnostic systems for precision detection of pathogens and viral threats. This review provides a com...

Bilirubin biosensors for liver disease management.

Clinica chimica acta; international journal of clinical chemistry
Bilirubin is a vital biomarker that plays a significant role in assessing liver function and diagnosing hemolytic disorders. While current detection methods are indeed sufficient for clinical practice, the accurate and timely detection of bilirubin l...

Development of an alcohol biosensor non-wear algorithm: laboratory-based machine learning and field-based deployment.

Scientific reports
Wrist-worn alcohol biosensors can continuously track alcohol consumption, but their measurements are disrupted when the device is removed. Left unaddressed, non-wear data compromises observations of alcohol use and subsequent predictions of intoxicat...

Challenges and Opportunities in Smart Biosensing for Biomanufacturing.

ACS synthetic biology
Traditional metabolic engineering has largely focused on the direct construction of synthetic metabolic pathways, often overlooking the critical role of regulation. In contrast, natural metabolic pathways are inherently tightly regulated, enabling ro...

Advanced smart bioelectronics for wound healing: biosensing, drug delivery, and artificial intelligence.

International journal of pharmaceutics
Chronic wounds represent a significant healthcare challenge characterized by complex pathophysiology and poor clinical outcomes. The latest progress in smart bioelectronic systems which include biosensing capabilities alongside controlled drug delive...

Hypersensitive pressure sensors inspired by scorpion mechanosensory mechanisms for near-body flow detection in intelligent robots.

Science advances
Sensitivity enhancement for pressure sensors over a broad linear range can improve sensing performance for a wide range of applications such as health monitoring and artificial intelligence. Here, inspired by the high-precision mechanosensory mechani...

SERS technology in virus Detection: Advances, challenges, and future perspectives.

Biosensors & bioelectronics
SERS has revolutionized viral detection with its high sensitivity and specificity. This review comprehensively explores the application progress, challenges, and future directions of SERS in viral detection. Firstly, the fundamental principles of SER...

Low-Cost Polyphenol-Polypyrrole Molecularly Imprinted Sensor for Point-of-Care Alzheimer's Detection.

ACS sensors
There is an urgent need for rapid, affordable diagnostics for Alzheimer's disease (AD), particularly those that can detect phosphorylated Tau 181 (p-tau181)─a key biomarker─directly in plasma. We present a scalable, label-free electrochemical biosens...

Advancing Whole-Cell Biosensors: Kinetics-Dependent Metabolic SERS Analytics for Pollutant Differentiation and Quantification.

Analytical chemistry
Whole-cell biosensors (WCBs), which detect targeting analytes through cellular responses, have become powerful tools for environmental monitoring. However, existing WCBs often rely on the single-channel low-dimension signal outputs (e.g., fluorescenc...