Glioblastoma (GBM) is the most common primary malignant brain tumor in adults. The standard treatment for GBM consists of surgical resection followed by concurrent chemoradiotherapy and adjuvant temozolomide. O-6-methylguanine-DNA methyltransferase (...
IEEE reviews in biomedical engineering
Jan 5, 2023
A state-of-the-art interdisciplinary survey on multi-modal radiogenomic approaches is presented involving applications to the diagnosis and personalized management of gliomas a common kind of brain tumors through noninvasive imaging integrated with g...
BACKGROUND: The O6-methylguanine-DNA methyltransferase (MGMT) is a deoxyribonucleic acid (DNA) repairing enzyme that has been established as an essential clinical brain tumor biomarker for Glioblastoma Multiforme (GBM). Knowing the status of MGMT met...
Today, as in every life-threatening disease, early diagnosis of brain tumors plays a life-saving role. The brain tumor is formed by the transformation of brain cells from their normal structures into abnormal cell structures. These formed abnormal ce...
BACKGROUND: Robot-assisted stereotactic biopsy is evolving: 3-dimensional intraoperative imaging tools and new frameless registration systems are spreading.
Cytopathology : official journal of the British Society for Clinical Cytology
Dec 25, 2022
BACKGROUND: Intraoperative pathological diagnosis of central nervous system (CNS) tumours is essential to planning patient management in neuro-oncology. Frozen section slides and cytological preparations provide architectural and cellular information...
OBJECTIVE: Preoperative diagnosis of diffuse midline glioma, H3 K27-altered (DMG-A) and midline high-grade glioma without H3 K27 alteration (DMG-W), as well as midline primary CNS lymphoma (PCNSL) in adults, is challenging but crucial. The aim of thi...
BACKGROUND: Supervised deep learning in radiology suffers from notorious inherent limitations: 1) It requires large, hand-annotated data sets; (2) It is non-generalizable; and (3) It lacks explainability and intuition. It has recently been proposed t...
PURPOSE: Volumetric assessments, such as extent of resection (EOR) or residual tumor volume, are essential criterions in glioma resection surgery. Our goal is to develop and validate segmentation machine learning models for pre- and postoperative mag...
The international journal of medical robotics + computer assisted surgery : MRCAS
Dec 12, 2022
BACKGROUND: Segmentation of brain tumours is a complex problem in medical image processing and analysis. It is a time-consuming and error-prone task. Therefore, computer-aided detection systems need to be developed to decrease physicians' workload an...
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