AIMC Topic: Breast Neoplasms

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Longitudinal interpretability of deep learning based breast cancer risk prediction.

Physics in medicine and biology
Deep-learning-based models have achieved state-of-the-art breast cancer risk (BCR) prediction performance. However, these models are highly complex, and the underlying mechanisms of BCR prediction are not fully understood. Key questions include wheth...

Machine Learning to Predict the Individual Risk of Treatment-Relevant Toxicity for Patients With Breast Cancer Undergoing Neoadjuvant Systemic Treatment.

JCO clinical cancer informatics
PURPOSE: Toxicity to systemic cancer treatment represents a major anxiety for patients and a challenge to treatment plans. We aimed to develop machine learning algorithms for the upfront prediction of an individual's risk of experiencing treatment-re...

Machine learning based radiomics model to predict radiotherapy induced cardiotoxicity in breast cancer.

Journal of applied clinical medical physics
PURPOSE: Cardiotoxicity is one of the major concerns in breast cancer treatment, significantly affecting patient outcomes. To improve the likelihood of favorable outcomes for breast cancer survivors, it is essential to carefully balance the potential...

Interactively Fusing Global and Local Features for Benign and Malignant Classification of Breast Ultrasound Images.

Ultrasound in medicine & biology
OBJECTIVE: Breast ultrasound (BUS) is used to classify benign and malignant breast tumors, and its automatic classification can reduce subjectivity. However, current convolutional neural networks (CNNs) face challenges in capturing global features, w...

Quantifying interpretation reproducibility in Vision Transformer models with TAVAC.

Science advances
Deep learning algorithms can extract meaningful diagnostic features from biomedical images, promising improved patient care in digital pathology. Vision Transformer (ViT) models capture long-range spatial relationships and offer robust prediction pow...

Automated Identification of Breast Cancer Relapse in Computed Tomography Reports Using Natural Language Processing.

JCO clinical cancer informatics
PURPOSE: Breast cancer relapses are rarely collected by cancer registries because of logistical and financial constraints. Hence, we investigated natural language processing (NLP), enhanced with state-of-the-art deep learning transformer tools and la...

Use and Comparison of Machine Learning Techniques to Discern the Protein Patterns of Autoantibodies Present in Women with and without Breast Pathology.

Journal of proteome research
Breast cancer (BC) has become a global health problem, ranking first in incidence and fifth in mortality in women around the world. Although there are some diagnostic methods for the disease, these are not sufficiently effective and are invasive. In ...

Development of two machine learning models to predict conversion from primary HER2-0 breast cancer to HER2-low metastases: a proof-of-concept study.

ESMO open
BACKGROUND: HER2-low expression has gained clinical relevance in breast cancer (BC) due to the availability of anti-HER2 antibody-drug conjugates for patients with HER2-low metastatic BC. The well-reported instability of HER2-low status during diseas...

Advanced analytical methods for multi-spectral transmission imaging optimization: enhancing breast tissue heterogeneity detection and tumor screening with hybrid image processing and deep learning.

Analytical methods : advancing methods and applications
Light sources exhibit significant absorption and scattering effects during the transmission through biological tissues, posing challenges in identifying heterogeneities in multi-spectral images. This paper introduces a fusion of techniques encompassi...