AIMC Topic: Carcinoma, Pancreatic Ductal

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Biomarkers, omics and artificial intelligence for early detection of pancreatic cancer.

Seminars in cancer biology
Pancreatic ductal adenocarcinoma (PDAC) is frequently diagnosed in its late stages when treatment options are limited. Unlike other common cancers, there are no population-wide screening programmes for PDAC. Thus, early disease detection, although ur...

Multiscale deep learning radiomics for predicting recurrence-free survival in pancreatic cancer: A multicenter study.

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
PURPOSE: This multicenter study aimed to develop and validate a multiscale deep learning radiomics nomogram for predicting recurrence-free survival (RFS) in patients with pancreatic ductal adenocarcinoma (PDAC).

Super-resolution deep-learning reconstruction with 1024 matrix improves CT image quality for pancreatic ductal adenocarcinoma assessment.

European journal of radiology
OBJECTIVES: To evaluate the efficiency of super-resolution deep-learning reconstruction (SR-DLR) optimized for helical body imaging in assessing pancreatic ductal adenocarcinoma (PDAC) using normal-resolution (NR) CT scanner.

Multiparametric MRI for Assessment of the Biological Invasiveness and Prognosis of Pancreatic Ductal Adenocarcinoma in the Era of Artificial Intelligence.

Journal of magnetic resonance imaging : JMRI
Pancreatic ductal adenocarcinoma (PDAC) is the deadliest malignant tumor, with a grim 5-year overall survival rate of about 12%. As its incidence and mortality rates rise, it is likely to become the second-leading cause of cancer-related death. The r...

Integrating artificial intelligence with endoscopic ultrasound in the early detection of bilio-pancreatic lesions: Current advances and future prospects.

Best practice & research. Clinical gastroenterology
The integration of Artificial Intelligence (AI) in endoscopic ultrasound (EUS) represents a transformative advancement in the early detection and management of biliopancreatic lesions. This review highlights the current state of AI-enhanced EUS (AI-E...

AI-Driven insights in pancreatic cancer imaging: from pre-diagnostic detection to prognostication.

Abdominal radiology (New York)
Pancreatic ductal adenocarcinoma (PDAC) is the third leading cause of cancer-related deaths in the United States, largely due to its poor five-year survival rate and frequent late-stage diagnosis. A significant barrier to early detection even in high...

Assessing the value of deep neural networks for postoperative complication prediction in pancreaticoduodenectomy patients.

PloS one
INTRODUCTION: Pancreaticoduodenectomy (PD) for patients with pancreatic ductal adenocarcinoma (PDAC) is associated with a high risk of postoperative complications (PoCs) and risk prediction of these is therefore critical for optimal treatment plannin...

Explainable machine learning identifies a polygenic risk score as a key predictor of pancreatic cancer risk in the UK Biobank.

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
BACKGROUND: Predicting the risk of developing pancreatic ductal adenocarcinoma (PDAC) is of paramount importance, given its high mortality rate. Current PDAC risk prediction models rely on a limited number of variables, do not include genetics, and h...

Computed tomography-based fully automated artificial intelligence model to predict extrapancreatic perineural invasion in pancreatic ductal adenocarcinoma.

International journal of surgery (London, England)
BACKGROUND: Extrapancreatic perineural invasion (EPNI) increases the risk of postoperative recurrence in pancreatic ductal adenocarcinoma (PDAC). This study aimed to develop and validate a computed tomography (CT)-based, fully automated preoperative ...