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Case-Control Studies

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Classification of Alzheimer's Disease Using Gaussian-Based Bayesian Parameter Optimization for Deep Convolutional LSTM Network.

Computational and mathematical methods in medicine
Alzheimer's disease (AD) is one of the most important causes of mortality in elderly people, and it is often challenging to use traditional manual procedures when diagnosing a disease in the early stages. The successful implementation of machine lear...

Artificial intelligence application versus physical therapist for squat evaluation: a randomized controlled trial.

Scientific reports
Artificial intelligence technology is becoming more prevalent in health care as a tool to improve practice patterns and patient outcomes. This study assessed ability of a commercialized artificial intelligence (AI) mobile application to identify and ...

Deep learning detects acute myeloid leukemia and predicts NPM1 mutation status from bone marrow smears.

Leukemia
The evaluation of bone marrow morphology by experienced hematopathologists is essential in the diagnosis of acute myeloid leukemia (AML); however, it suffers from a lack of standardization and inter-observer variability. Deep learning (DL) can proces...

Deep Learning Predicts Interval and Screening-detected Cancer from Screening Mammograms: A Case-Case-Control Study in 6369 Women.

Radiology
Background The ability of deep learning (DL) models to classify women as at risk for either screening mammography-detected or interval cancer (not detected at mammography) has not yet been explored in the literature. Purpose To examine the ability of...

Detection of sarcopenic obesity and prediction of long-term survival in patients with gastric cancer using preoperative computed tomography and machine learning.

Journal of surgical oncology
BACKGROUND: Previous studies evaluating the prognostic value of computed tomography (CT)-derived body composition data have included few patients. Thus, we assessed the prevalence and prognostic value of sarcopenic obesity in a large population of ga...

Risk prediction of diabetic nephropathy using machine learning techniques: A pilot study with secondary data.

Diabetes & metabolic syndrome
AIMS: This research work presented a comparative study of machine learning (ML), including two objectives: (i) determination of the risk factors of diabetic nephropathy (DN) based on principal component analysis (PCA) via different cutoffs; (ii) pred...

An approach to rapidly assess sepsis through multi-biomarker host response using machine learning algorithm.

Scientific reports
Sepsis is a life-threatening condition and understanding the disease pathophysiology through the use of host immune response biomarkers is critical for patient stratification. Lack of accurate sepsis endotyping impedes clinicians from making timely d...

Deep learning-based gene selection in comprehensive gene analysis in pancreatic cancer.

Scientific reports
The selection of genes that are important for obtaining gene expression data is challenging. Here, we developed a deep learning-based feature selection method suitable for gene selection. Our novel deep learning model includes an additional feature-s...

Interleukin-37 gene polymorphism and susceptibility to pulmonary tuberculosis among Iraqi patients.

The Indian journal of tuberculosis
BACKGROUND: Control of tuberculosis (TB) depends on a balance between host's immune factors and bacterial evasion strategies. Interleukin-37 (IL-37) is among the immunomodulatory factors that have been proposed to influence susceptibility to tubercul...

Using normative modelling to detect disease progression in mild cognitive impairment and Alzheimer's disease in a cross-sectional multi-cohort study.

Scientific reports
Normative modelling is an emerging method for quantifying how individuals deviate from the healthy populational pattern. Several machine learning models have been implemented to develop normative models to investigate brain disorders, including regre...