AIMC Topic: Celecoxib

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Synergistic analgesic effects of astaxanthin combined with celecoxib on a mouse bone cancer pain model: From behavioral validation to target prediction.

International immunopharmacology
Bone cancer pain (BCP) is a complex condition that severely affects patients' quality of life, and its treatment remains challenging. Astaxanthin, a potent antioxidant with anti-inflammatory and neuroprotective effects, and celecoxib, a selective COX...

Identification of immune patterns in idiopathic pulmonary fibrosis patients driven by PLA2G7-positive macrophages using an integrated machine learning survival framework.

Scientific reports
Patients with advanced idiopathic pulmonary fibrosis (IPF), a complex and incurable lung disease with an elusive pathology, are nearly exclusive candidates for lung transplantation. Improved identification of patient subtypes can enhance early diagno...

Application of unfolded principal component analysis-radial basis function neural network for determination of celecoxib in human serum by three-dimensional excitation-emission matrix fluorescence spectroscopy.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
This study describes a simple and rapid approach of monitoring celecoxib (CLX). Unfolded principal component analysis-radial basis function neural network (UPCA-RBFNN) and excitation-emission spectra were combined to develop new model in the determin...

Development and validation of a LC-FL method for the simultaneous determination of doxorubicin and celecoxib in nanoparticulate fixed dose combination (NanoFDC).

Die Pharmazie
An isocratic reversed phase HPLC method for the simultaneous determination of doxorubicine (DOX) and celecoxib (CXB) out of a nanoparticulate fixed dose combination (NanoFDC) was developed and validated. Linearity of the results was demonstrated from...