FASEB journal : official publication of the Federation of American Societies for Experimental Biology
40341625
The Japanese Kampo medicine Boi-ogi-to (BOT) is known as an effective therapeutic agent for edema and nephrosis by promoting the excretion of excess body fluids. Despite its empirical effectiveness, scientific evidence supporting its effectiveness re...
Although label-free cell sorting is desirable for providing pristine cells for further analysis or use, current approaches lack molecular specificity and speed. Here, we combine real-time fluorescence and deformability cytometry with sorting based on...
Measuring the physical size of a cell is valuable in understanding cell growth control. Current single-cell volume measurement methods for mammalian cells are labor intensive, inflexible and can cause cell damage. We introduce CTRL: Cell Topography R...
Dynamic light scattering (DLS) is an essential technique used for assessing the size of the particles in suspension, covering the range from nanometers to microns. Although it has been very well established for quite some time, improvement can still ...
Genetic studies have recently highlighted the importance of fat distribution, as well as overall adiposity, in the pathogenesis of obesity-associated diseases. Using a large study (n = 1,288) from 4 independent cohorts, we aimed to investigate the re...
Herein, we implement and access machine learning architectures to ascertain models that differentiate healthy from apoptotic cells using exclusively forward (FSC) and side (SSC) scatter flow cytometry information. To generate training data, colorecta...
Cytometry. Part A : the journal of the International Society for Analytical Cytology
33891370
The Coulter principle is a widespread technique for sizing red blood cells (RBCs) in hematological analyzers. It is based on the monitoring of the electrical perturbations generated by cells passing through a micro-orifice, in which a concentrated el...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
38083674
Chronic hypoxia is known to be a major cause of neurite length retraction followed be degeneration. Specifically, laser scanning confocal microscopy (LSCM) based-contrast imaging is used for monitoring neuronal morphology under hypoxic condition. Alt...
Medical & biological engineering & computing
37532907
Medical image processing has become increasingly important in recent years, particularly in the field of microscopic cell imaging. However, accurately counting the number of cells in an image can be a challenging task due to the significant variation...
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference
40039040
Automated detection of infected insect cells is one of the crucial tasks in the field of recombinant protein production and vaccine development. The major challenge lies in manual segmentation of cells and quantifying cell size distribution is tediou...